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Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil
Salles, Nanci Alves; Nishiya, Anna Shoko; Ferreira, Suzete Cleusa; Rocha, Vanderson Geraldo; Mendrone-Junior, Alfredo.
  • Salles, Nanci Alves; Fundação Pró-Sangue. Hemocentro de São Paulo. São Paulo. BR
  • Nishiya, Anna Shoko; Fundação Pró-Sangue. Hemocentro de São Paulo. São Paulo. BR
  • Ferreira, Suzete Cleusa; Fundação Pró-Sangue. Hemocentro de São Paulo. São Paulo. BR
  • Rocha, Vanderson Geraldo; Fundação Pró-Sangue. Hemocentro de São Paulo. São Paulo. BR
  • Mendrone-Junior, Alfredo; Fundação Pró-Sangue. Hemocentro de São Paulo. São Paulo. BR
Rev. Soc. Bras. Med. Trop ; 52: e20180432, 2019. tab
Article in English | LILACS | ID: biblio-1003137
ABSTRACT
Abstract By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegative HIV-viremic donations were detected. The NAT yield rate per million donations was 3.34 for HIV, and the acute HIV-1 infections detected are described, followed by a brief review of the situation in Brazil.
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Full text: Available Index: LILACS (Americas) Main subject: Blood Donors / DNA, Viral / RNA, Viral / HIV Infections / HIV-1 / Nucleic Acid Amplification Techniques Type of study: Diagnostic study Limits: Adult / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Pró-Sangue/BR

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Full text: Available Index: LILACS (Americas) Main subject: Blood Donors / DNA, Viral / RNA, Viral / HIV Infections / HIV-1 / Nucleic Acid Amplification Techniques Type of study: Diagnostic study Limits: Adult / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fundação Pró-Sangue/BR