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What do Cochrane systematic reviews say about the management of irritable bowel syndrome?
Pacheco, Rafael Leite; Roizenblatt, Arnaldo; Discipline of Evidence-Based MedicineGóis, Aécio Flávio Teixeira de; Latorraca, Carolina de Oliveira Cruz; Mota, Carolina Frade Magalhães Girardin Pimentel; Discipline of Evidence-Based MedicineRiera, Rachel.
Affiliation
  • Pacheco, Rafael Leite; Universidade Federal de São Paulo. Evidence-Based Health Program. São Paulo. BR
  • Roizenblatt, Arnaldo; Universidade Federal de São Paulo. Escola Paulista de Medicina. São Paulo. BR
  • Discipline of Evidence-Based MedicineGóis, Aécio Flávio Teixeira de; Universidade Federal de São Paulo. Escola Paulista de Medicina. Discipline of Evidence-Based MedicineGóis, Aécio Flávio Teixeira de. São Paulo. BR
  • Latorraca, Carolina de Oliveira Cruz; Universidade Federal de São Paulo. Evidence-Based Health Program. São Paulo. BR
  • Mota, Carolina Frade Magalhães Girardin Pimentel; Universidade Federal de São Paulo. Escola Paulista de Medicina. Discipline of Evidence-Based Medicine. São Paulo. BR
  • Discipline of Evidence-Based MedicineRiera, Rachel; Universidade Federal de São Paulo. Escola Paulista de Medicina. Discipline of Evidence-Based MedicineRiera, Rachel. São Paulo. BR
São Paulo med. j ; 137(1): 82-91, Jan.-Feb. 2019. tab
Article in En | LILACS | ID: biblio-1004735
Responsible library: BR1.1
ABSTRACT
ABSTRACT

BACKGROUND:

Irritable bowel syndrome (IBS) is a clinical disorder associated with high socioeconomic burden. Despite its importance, management of IBS remains difficult and several interventions have been hypothesized as beneficial for this condition. This study identified and summarized all Cochrane systematic reviews (SRs) about the effects of interventions for managing IBS patients. DESIGN AND

SETTING:

Review of systematic reviews, carried out in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).

METHODS:

Review of Cochrane SRs addressing interventions for IBS.

RESULTS:

We included six SRs assessing acupuncture, bulking agents, antispasmodics, antidepressants, herbal medicines, homeopathy, hypnotherapy and psychological therapy for IBS. The certainty of evidence ranged from unknown to moderate, mainly due to imprecision in the estimates and high risk of bias from the primary studies included. There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life, compared with sham acupuncture. There was also very low certainty of evidence that homeopathic asafoetida, used alone or in association with nux, was better than placebo regarding self-reported overall improvement.

CONCLUSION:

There was moderate certainty of evidence that acupuncture had no important benefit regarding improvement of symptoms and quality of life. Further well-designed and well-conducted randomized clinical trials are needed in order to reduce the uncertainties regarding the most commonly used interventions for patients with IBS.
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Full text: 1 Index: LILACS Main subject: Disease Management / Irritable Bowel Syndrome / Systematic Reviews as Topic Type of study: Clinical_trials / Systematic_reviews Limits: Humans Language: En Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / MEDICINA / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2019 Type: Article

Full text: 1 Index: LILACS Main subject: Disease Management / Irritable Bowel Syndrome / Systematic Reviews as Topic Type of study: Clinical_trials / Systematic_reviews Limits: Humans Language: En Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / MEDICINA / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2019 Type: Article