Hypoglycemia caused by co-secretion of insulin from lung tumor and cardia cancer: first case report
São Paulo med. j
;
137(1): 100-103, Jan.-Feb. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1004736
ABSTRACT
ABSTRACT CONTEXT Non-islet-cell-tumor-induced hypoglycemia (NICTH) is caused on rare occasions by secretion of insulin from tumor cells that are reported to have a single tissue origin. CASE REPORT A 67-year-old male patient had cardia adenocarcinoma and concomitant lung adenocarcinoma with extensive metastases and repeated episodes of intractable hypoglycemia. Immunohistochemical staining for insulin showed that lung adenocarcinoma stained positive and gastric cardia adenocarcinoma stained weakly positive. These results indicate that tumor cells of different tissue origins co-secreted insulin. CONCLUSIONS:
This is the first report on intractable hypoglycemia due to co-secretion of insulin from two kinds of primary tumor cells in a single patient.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Stomach Neoplasms
/
Cardia
/
Adenocarcinoma
/
Hypoglycemia
/
Lung Neoplasms
Type of study:
Diagnostic study
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2019
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
General Navy Hospital of PLA/CN
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