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Cancer incidence in the cohort exposed to Cesium-137 accident in Goiânia (Brazil) in 1987
Curado, Maria Paula; Oliveira, Max Moura de; Valverde, Nelson José de Lima; Cruz, Aparecido Divino da.
  • Curado, Maria Paula; Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center. São Paulo. BR
  • Oliveira, Max Moura de; Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center. São Paulo. BR
  • Valverde, Nelson José de Lima; Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center. São Paulo. BR
  • Cruz, Aparecido Divino da; Pontifical Catholic University of Goiás. Laboratory of Human Cytogenetics and Molecular Genetics. Goiânia. BR
J. Health Biol. Sci. (Online) ; 7(3): 228-232, jul.-set. 2019.
Article in English | LILACS | ID: biblio-1005601
ABSTRACT
Objective:to describe the incidence of cancer cases in the direct victims of the accident, Groups I and II, and compare with overall cancer incidence rates for the population of Goiânia. Method: A descriptive study is presented herein, on the cohort of patients directly exposed and contaminated (Groups I and II) during the cesium-137 accident, which occurred in Goiania (Midwest Brazil) in 1987. The incident cases of malignant neoplasms diagnosed between 1988 and 2017 are described. Analysis included calculation of the Incidence Rate Ratio (IRR) with 95% confidence intervals (CI95%), according to gender. Results: In the 30-year period (1987-2017) following individual exposure, there were seven cancer cases in six directly exposed victims of the cesium-137 accident. Of these, five neoplasms occurred in men, in the esophagus (1), prostrate (3), bladder (1), and two in women, involving breast cancer (1) and skin melanoma (1). The accumulated incidence rates in the direct victims of the Cesium-137 accident were 327.9/100,000 for men and 148.6/100,000 for women. For the overall population of Goiânia, rates were 221.4/100,000 and 231.2/100,000 in men and women, respectively. The ratios of brute incidence rates (direct victims of Cesium-137/population of Goiânia) were 1.5 (IC95%:0.4;5.9) in men and 0.6 (IC95%:0.1;3.8) in women, with no statistically significant differences. Conclusion: Cancer incidence in the direct victims of the Cesium-137 accident (Groups I and II), according to sex, was not different from the incidence in those not exposed to Cesium-137 in the municipality of Goiânia. Cancer risk was similar to that of the general population of the municipality of Goiânia
RESUMO
Objetivo: descrever a incidência de casos de câncer nas vítimas diretas do acidente Grupo I e II e comparar com as taxas de incidência de câncer na população de Goiânia. Método: Estudo descritivo da coorte de pacientes diretamente expostos e contaminados (Grupos I e II), no acidente com Césio 137, ocorrido em Goiânia (Brasil), em 1987. Descrevemos os casos incidentes de neoplasia maligna diagnosticados no período entre 1988 e 2017. Foram calculados a razão das taxas de incidência e os intervalos de confiança de 95% (IC95%), segundo o sexo na população de estudo. Resultados: No período de 30 anos (1987-2017), ocorreram sete casos de câncer, em seis vítimas diretas do acidente pelo césio-137. Desses, cinco ocorreram em homens (esôfago [1], próstata [3] e bexiga [1]) e dois, em mulheres (mama [1] e melanoma da pele [1]). As taxas de incidência acumulada nas vítimas diretas do Césio-137 foram de 327,9/100,000 entre homens e de 148,6/100,000 entre as mulheres. Na população de Goiânia, as taxas foram de 221,4/100,000 e 231,2/100,000 em homens e mulheres, respectivamente. As razões das taxas de incidência bruta (vítimas diretas do Césio-137/população de Goiânia) foram 1,5 (IC95%:0,4;5,9) em homens e 0,6 (IC95%:0,1;3,8) em mulheres, não houve diferenças estatisticamente significativas. Conclusão: A incidência de câncer nas vítimas diretas do acidente pelo Césio 137 (Grupos I e II), segundo o sexo, não foi diferente da população não exposta ao Césio-137 do município de Goiânia; portanto, o risco de câncer foi semelhante ao da população geral do Município de Goiânia.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Cesium Type of study: Incidence study / Risk factors Country/Region as subject: South America / Brazil Language: English Journal: J. Health Biol. Sci. (Online) Journal subject: Ciˆncias da Sa£de / Disciplinas das Ciˆncias Biol¢gicas Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center/BR / Pontifical Catholic University of Goiás/BR

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Full text: Available Index: LILACS (Americas) Main subject: Cesium Type of study: Incidence study / Risk factors Country/Region as subject: South America / Brazil Language: English Journal: J. Health Biol. Sci. (Online) Journal subject: Ciˆncias da Sa£de / Disciplinas das Ciˆncias Biol¢gicas Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center/BR / Pontifical Catholic University of Goiás/BR