Second-to-fourth digit ratio and seborrheic dermatitis in males: a cross-sectional study*
An. bras. dermatol
;
94(3): 327-330, May-June 2019. tab
Article
in English
| LILACS
| ID: biblio-1011107
ABSTRACT
Abstract Background:
Seborrheic dermatitis is a common disease characterized by the erythematous plaques with oily-yellow desquamation. Increased sebaceous gland activity by androgenic hormones has played a role in the etiology of the disease. The second-to-fourth digit (2D4D) ratio is thought to be a marker of prenatal androgen exposure.Objectives:
To investigate the association between 2D4D ratios and seborrheic dermatitis in a male population.Methods:
Healthy male controls and patients with seborrheic dermatitis were included in this study. One hundred seborrheic dermatitis patients and 120 healthy controls, aged 17-59, were enrolled. A digital Vernier caliper was used to measure the finger lengths. Seborrheic dermatitis severity was assessed using the Seborrheic Dermatitis Area and Severity Index (SDASI).Results:
The 2D4D ratios of the patients (x = 0.977) were significantly lower than those of the controls (x = 1.050) for right hands (t = 6.948; p = 0.000; > 0.05). No similar relationship was found between the 2D4D ratio for left hands (t = 0.901; p = 0.368; > 0.05). Seborrheic dermatitis severity was negatively correlated with 2D4D ratios of right hands (r = -0.391; p = 0.000-0.05). Studylimitations:
One of the main limitations of this study was the small sample, which got a head of us from acquiring certain findings about the 2D4D ratio and seborrheic dermatitis. The other limitation is that the patient selection did not reflect the general population, as a single clinic was studied.Conclusion:
To the authors' knowledge, this is the first study examining the relationship between 2D4D ratios and seborrheic dermatitis. The result of this study may indicate a line of investigation and can support the theory of prenatal androgen exposure.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Dermatitis, Seborrheic
/
Fingers
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2019
Type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Selcuk University/TR
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