Testosterone therapy for women with low sexual desire: a position statement from the Brazilian Society of Endocrinology and Metabolism
Arch. endocrinol. metab. (Online)
;
63(3): 190-198, May-June 2019. tab
Article
in English
| LILACS
| ID: biblio-1011166
ABSTRACT
ABSTRACT Objective To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription. Arch Endocrinol Metab. 2019;63(3)190-8
Full text:
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Index:
LILACS (Americas)
Main subject:
Sexual Dysfunction, Physiological
/
Testosterone
/
Androgens
/
Libido
Type of study:
Practice guideline
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Arch. endocrinol. metab. (Online)
Journal subject:
Endocrinology
/
Metabolism
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Departamento de Fisiologia Endócrina e Fisiologia/BR
/
Instituto de Medicina Integral Professor Fernando Figueira/BR
/
Pontifícia Universidade Católica do Rio de Janeiro/BR
/
Universidade Federal de Santa Catarina/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade de São Paulo/BR
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