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Testicular mixed germ cell tumor presenting with seizure as the initial symptom: a case report and literature review
Syu, Syuan-Hao; Chang, Chia-Lun; Shih, Hung-Jen.
  • Syu, Syuan-Hao; Taipei Medical University. Wan Fang Hospital. Department of Urology. Taipei City. TW
  • Chang, Chia-Lun; Taipei Medical University. Wan Fang Hospital. Department of Hematology. Taipei City. TW
  • Shih, Hung-Jen; Taipei Medical University. Wan Fang Hospital. Department of Urology. Taipei City. TW
Int. braz. j. urol ; 45(3): 629-633, May-June 2019. graf
Article in English | LILACS | ID: biblio-1012332
ABSTRACT
Abstract Most patients with testicular germ cell tumor present with a painless scrotal mass. We report a 19-year-old patient who presented with neurological complains. Rapid clinical progression to coma was noted during the staging work up. A diagnosis of testicular mixed germ cell tumor with multiorgan metastasis (lymph node, lung, liver and brain) was made. Patients with brain metastasis should receive chemotherapy alone or combined with surgery or radiotherapy. Because the clinical symptoms deteriorated quickly, surgery was used upfront followed by chemotherapy and radiotherapy for the brain tumor. After the first stage of treatment, the clinical symptoms, tumor markers and imaging findings were improved. The residual brain tumor was eliminated by chemotherapy, and only sparse degenerated tumor cells were noted in the brain tissue. Longer follow up is required to assess the impact of our treatment strategy.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Seizures / Testicular Neoplasms / Brain Neoplasms / Neoplasms, Germ Cell and Embryonal Type of study: Diagnostic study Limits: Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2019 Type: Article Affiliation country: Taiwan Institution/Affiliation country: Taipei Medical University/TW

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Full text: Available Index: LILACS (Americas) Main subject: Seizures / Testicular Neoplasms / Brain Neoplasms / Neoplasms, Germ Cell and Embryonal Type of study: Diagnostic study Limits: Humans / Male Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2019 Type: Article Affiliation country: Taiwan Institution/Affiliation country: Taipei Medical University/TW