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Uso de la Fibrina Rica en Plaquetas Inyectable (i-PRF) en Defectos Infra Óseos en Terapia Periodontal no Quirúrgica. Reporte de Dos Casos / Use of Injectable Platelet-Rich Fibrin (i-PRF) in Infra Osseous Defects in Non-Surgical Periodontal Therapy. Report of Two Cases
Correa, A. J; Alister, J. P; Manterola, C.
  • Correa, A. J; Universidad de La Frontera. Temuco. CL
  • Alister, J. P; Universidad de La Frontera. Temuco. CL
  • Manterola, C; Universidad de La Frontera. Temuco. CL
Int. j. odontostomatol. (Print) ; 13(3): 271-274, set. 2019. graf
Article in Spanish | LILACS | ID: biblio-1012421
RESUMEN
RESUMEN Entre los concentrados plaquetarios de segunda generación, ha suscitado creciente interés, el uso de fibrina rica en plaquetas y leucocitos inyectable (i-PRF); que se obtiene a partir de la centrifugación inmediata de sangre venosa del propio individuo, y que aporta concentraciones elevadas de factor de crecimiento vascular endotelial, factor de crecimiento transformante beta, y factor de crecimiento derivado de plaquetas, entre otras proteínas que inician y coordinan el proceso reparativo. Su nula citotoxicidad y consistencia líquida abren un nuevo campo de estudio y experimentación en el ámbito de la Cirugía Oral y de la Periodoncia, como sustancia para irrigar. El objetivo de este manuscrito fue reportar el uso del i-PRF como irrigador subgingival en el tratamiento periodontal convencional de defectos infra óseos con 6 meses de seguimiento. En ambos casos, se verificó un efecto positivo de irrigación, lo que abre el debate al uso de productos farmacéuticos tradicionales como la clorhexidina versus preparados autólogos sin efectos adversos reportados a la fecha.
ABSTRACT
ABSTRACT Second generation platelet concentrates include the use of injectable platelet-rich fibrin (i-PRF), which has generated increasing interest because it is derived from immediate centrifugation of venous blood from the patients themselves. It provides high concentrations of vascular endothelial growth factor, transforming growth factor beta, and platelet-derived growth factor, among other proteins that initiate and coordinate the healing process. Its null cytotoxicity and liquid consistency has opened new research lines in the field of oral surgery and periodontics, as an irrigation substance. The aim of this manuscript was to report the use of i-PRF, as a subgingival irrigator in conventional periodontal treatment of infra osseous defects, with six months follow-up. In both cases, a positive effect of irrigation was confirmed. These findings, open the debate as regards the use of traditional pharmaceutical products (such as chlorhexidine), versus autonomous preparations without adverse effects reported to date.
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Full text: Available Index: LILACS (Americas) Main subject: Periodontics / Regeneration / Bone Substitutes / Intercellular Signaling Peptides and Proteins / Platelet-Rich Fibrin Limits: Adult / Aged / Aged80 / Female / Humans Language: Spanish Journal: Int. j. odontostomatol. (Print) Journal subject: Dentistry Year: 2019 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de La Frontera/CL

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Full text: Available Index: LILACS (Americas) Main subject: Periodontics / Regeneration / Bone Substitutes / Intercellular Signaling Peptides and Proteins / Platelet-Rich Fibrin Limits: Adult / Aged / Aged80 / Female / Humans Language: Spanish Journal: Int. j. odontostomatol. (Print) Journal subject: Dentistry Year: 2019 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de La Frontera/CL