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Aerobic exercise effects in renal function and quality of life of patients with advanced chronic kidney disease
Calvo-Lobo, César; Neyra-Bohorquez, Pierre Phillippe; Seco-Calvo, Jesús.
  • Calvo-Lobo, César; Universidad de León. Institute of Biomedicine (IBIOMED). Nursing and Physical Therapy Department. ES
  • Neyra-Bohorquez, Pierre Phillippe; Galdakao Hospital. Nephrology Unit. ES
  • Seco-Calvo, Jesús; University of León. Institute of Biomedicine (IBIOMED). University of the Basque Country. ES
Rev. Assoc. Med. Bras. (1992) ; 65(5): 657-662, May 2019. tab, graf
Article in English | LILACS | ID: biblio-1012955
ABSTRACT
SUMMARY

BACKGROUND:

To date, the therapeutic effects of exercise have not yet been evaluated regarding renal function parameters and quality of life specifically in patients with advanced chronic kidney disease. Thus, the study aim was to evaluate the effects of aerobic exercise in renal function and quality of life in patients with advanced chronic kidney disease.

METHODS:

A quasi-experimental prospective study [NCT03301987] was carried out. Nine patients with advanced chronic kidney disease were recruited from a hospital nephrology unit. Kidney function parameters such as creatinine, creatinine clearance, urea clearance, glomerular filtration rate, and creatinine/weight proportion, as well as the Kidney Disease Quality of Life SF-36 (KDQoL-SF36) were measured at baseline and after 1 month of aerobic exercise.

RESULTS:

Significant increases (P <.05) were observed for creatinine/weight proportion as well as symptoms, effects, charge, and physical domains of the KDQoL-SF36 after 1 month of therapeutic exercise. The other parameters did not show any statistically significant difference (P >.05).

CONCLUSIONS:

Aerobic exercise may cause improvements in renal function and quality of life of patients with advanced chronic kidney disease. Further studies about therapeutic exercise protocols specifically in patients with advanced stages of chronic kidney disease should be carried out in order to study their effectiveness and safety.
RESUMO
RESUMO

OBJETIVO:

Até o momento, os efeitos do exercício terapêutico ainda não tinham sido avaliados quanto aos parâmetros de função renal e qualidade de vida em pacientes com doença renal crônica avançada, especificamente. Assim, o objetivo do estudo foi avaliar os efeitos do exercício aeróbico na função renal e na qualidade de vida em pacientes com doença renal crônica avançada.

MÉTODOS:

Um estudo prospectivo quase experimental [NCT03301987] foi realizado. Nove pacientes com doença renal crônica avançada foram recrutados de uma unidade de nefrologia hospitalar. Parâmetros de função renal como creatinina, depuração de creatinina, liberação de ureia, taxa de filtração glomerular e creatinina/peso, bem como a qualidade de vida da doença renal SF-36 (KDQoL-SF36) foram medidos no início e após um mês de atividade aeróbica.

RESULTADOS:

Aumentos significativos (P<0,05) foram mostrados para a proporção de creatinina/peso, bem como sintomas, efeitos, carga e domínios físicos do KDQoL-SF36 após um mês de exercício terapêutico. Os demais parâmetros não apresentaram diferença estatisticamente significante (P>0,05).

CONCLUSÕES:

O exercício aeróbico pode produzir melhorias na função renal e na qualidade de vida de pacientes com doença renal crônica avançada. Especificamente, novos estudos sobre protocolos de exercícios terapêuticos em pacientes com estágios avançados de doença renal crônica devem ser realizados a fim de estudar sua eficácia e segurança.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Quality of Life / Exercise / Renal Insufficiency, Chronic / Exercise Therapy Type of study: Practice guideline / Observational study Limits: Aged / Female / Humans / Male Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Spain Institution/Affiliation country: Galdakao Hospital/ES / Universidad de León/ES / University of León/ES

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Full text: Available Index: LILACS (Americas) Main subject: Quality of Life / Exercise / Renal Insufficiency, Chronic / Exercise Therapy Type of study: Practice guideline / Observational study Limits: Aged / Female / Humans / Male Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Spain Institution/Affiliation country: Galdakao Hospital/ES / Universidad de León/ES / University of León/ES