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Dermatoses in parkinsonism: the importance of multidisciplinary follow-up
Antunes, Isadora; Purim, Kátia Sheylla Malta; Grande, Luara Leticia; Alberton, Nathália Cristina; Navarro, Tatiana Francinne Regis; Winckler, Thereza Cristina d'Ávila.
  • Antunes, Isadora; Positivo University. Curitiba. BR
  • Purim, Kátia Sheylla Malta; Positivo University. Curitiba. BR
  • Grande, Luara Leticia; Positivo University. Curitiba. BR
  • Alberton, Nathália Cristina; Positivo University. Curitiba. BR
  • Navarro, Tatiana Francinne Regis; Positivo University. Curitiba. BR
  • Winckler, Thereza Cristina d'Ávila; Positivo University. Curitiba. BR
Rev. Assoc. Med. Bras. (1992) ; 65(6): 791-795, June 2019. tab, graf
Article in English | LILACS | ID: biblio-1012980
ABSTRACT
Summary Parkinsonism is characterized by bradykinesia with rigidity and/or resting tremor, in addition to non-motor symptoms, which include dermatological manifestations. The objective of this study is to evaluate the main dermatoses in patients with parkinsonism found at the Philanthropic Association of Curitiba - PR. A cross-sectional descriptive study was carried out with the application of a questionnaire and dermatological evaluation of the patients. The sample consisted of 386 patients and was composed mainly by men (55.4%), between 60-74 years old (51.6%), with complete primary education (45.3%), disease diagnosis time between 5-10 years (35%) and in use of medication (96.6%). The most prevalent dermatoses were pigmented nevus (36.3%), warts (25.1%), actinic keratosis (22%), seborrheic keratosis (21.5%), seborrheic dermatitis (20.5%), and rosacea (19.2%). Among the 13 cases (3.4%) of malignant cutaneous neoplasms confirmed by biopsy, 2 were melanomas. Regarding patients' sex, there was a higher prevalence of inflammatory dermatoses (OR 1.64, 95% CI 1.08-2.51, p = 0.025) and benign cutaneous neoplasms (OR 1.77, 95% CI 1.16-2.69, p = 0.01) in men. As to age, patients aged between 60-74 years had more pre-malignant skin lesions (OR 2.60, 95% CI 1.05-6.44, p <0.001) and seborrheic keratosis (OR 2.52, 95% CI 1.02-6.25, p = 0.001) and, in those older than 75 years, actinic keratosis was more frequent (OR 5.43, 95% CI 2.17-13.6, p <0.001). The results of the study show that it is fundamental to dermatologically evaluate and monitor these patients, aiming at diagnosis and early treatment of lesions, especially of skin cancer.
RESUMO
RESUMO Parkinsonismo é caracterizado por bradicinesia e/ou tremor de repouso, além de sintomas não motores, entre os quais se destacam as manifestações dermatológicas. O objetivo desse trabalho é conhecer as principais dermatoses em pacientes portadores de parkinsonismo atendidos em uma associação filantrópica de Curitiba/PR. Foi realizado um estudo descritivo transversal com aplicação de questionário e avaliação dermatológica dos pacientes. A amostra estudada consistiu de 386 pacientes e foi composta principalmente por homens brancos (55,4%), entre 60-74 anos (51,6%), ensino fundamental completo (45,3%), tempo de diagnóstico da doença entre 5-10 anos (35%) e em uso de medicação (96,6%). As dermatoses mais encontradas na inspeção dermatológica foram manchas pigmentadas (36,3%), verrugas (25,1%), ceratose actínica (22%), ceratose seborreica (21,5%), dermatite seborreica (20,5%) e rosácea (19,2%). Entre os 11 casos (2,8%) de neoplasias cutâneas malignas confirmados por biópsia, dois eram melanomas. Em relação ao sexo, houve prevalência em homens de dermatoses inflamatórias (OR 1,64, IC 95% 1,08-2,51; p=0,025) e neoplasias cutâneas benignas (OR 1,77, IC 95% 1,16-2,69; p=0,01). Quanto à idade, pacientes entre 60-74 anos apresentaram mais lesões cutâneas pré-malignas (OR 2,60, IC 95% 1,05-6,44; p<0,001) e a ceratose seborreica (OR 2,52, IC 95% 1,02-6,25; p=0,001); naqueles acima de 75 anos foi mais frequente a ceratose actínica (OR 5,43, IC 95% 2,17-13,6; p<0,001). Os resultados encontrados no estudo evidenciam que são fundamentais a avaliação e o monitoramento dermatológico desses pacientes, visando diagnóstico e tratamento precoce das lesões, em especial do câncer de pele.
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Full text: Available Index: LILACS (Americas) Main subject: Skin Diseases / Parkinsonian Disorders Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Positivo University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Skin Diseases / Parkinsonian Disorders Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Positivo University/BR