A case of chronic and relapsing paget disease of the vulva
Rev. bras. ginecol. obstet
;
41(6): 412-416, June 2019. graf
Article
in English
| LILACS
| ID: biblio-1013624
ABSTRACT
Abstract Extramammary Paget disease is a rare neoplastic condition that more commonly affects postmenopausal Caucasian women. Although the vulvar area is the most frequently affected location, it corresponds solely to 1 to 2% of all vulvar malignancies. A 72-year-old female patient was observed in our outpatient clinic with a 2-year history of an erythematous and pruritic plaque on the vulva. Histopathology and immunohistochemistry studies were compatible with extramammary Paget disease of the vulva. Associated neoplastic conditions were excluded. Due to multiple relapses, the patient was submitted to three surgical interventions, including a total vulvectomy, and to external radiotherapy. The present case illustrates the chronic and recurrent nature of extramammary Paget disease despite aggressive procedures as well as the challenge in obtaining tumor-free resection margins.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Vulvar Neoplasms
/
Paget Disease, Extramammary
/
Vulvectomy
/
Imiquimod
/
Neoplasm Recurrence, Local
/
Antineoplastic Agents
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Rev. bras. ginecol. obstet
Journal subject:
Gynecology
/
Obstetrics
Year:
2019
Type:
Article
Affiliation country:
Portugal
Institution/Affiliation country:
Hospital de Santa Maria/PT
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