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A case of chronic and relapsing paget disease of the vulva
Bouceiro-Mendes, Rita; Mendonça-Sanches, Maria; Soares-de-Almeida, Luís; Correia-Fonseca, Isabel.
  • Bouceiro-Mendes, Rita; Hospital de Santa Maria. Centro Hospitalar Universitário Lisboa Norte. Department of Dermatovenereology. Lisboa. PT
  • Mendonça-Sanches, Maria; Hospital de Santa Maria. Centro Hospitalar Universitário Lisboa Norte. Department of Dermatovenereology. Lisboa. PT
  • Soares-de-Almeida, Luís; Hospital de Santa Maria. Centro Hospitalar Universitário Lisboa Norte. Department of Dermatovenereology. Lisboa. PT
  • Correia-Fonseca, Isabel; Hospital de Santa Maria. Centro Hospitalar Universitário Lisboa Norte. Department of Dermatovenereology. Lisboa. PT
Rev. bras. ginecol. obstet ; 41(6): 412-416, June 2019. graf
Article in English | LILACS | ID: biblio-1013624
ABSTRACT
Abstract Extramammary Paget disease is a rare neoplastic condition that more commonly affects postmenopausal Caucasian women. Although the vulvar area is the most frequently affected location, it corresponds solely to 1 to 2% of all vulvar malignancies. A 72-year-old female patient was observed in our outpatient clinic with a 2-year history of an erythematous and pruritic plaque on the vulva. Histopathology and immunohistochemistry studies were compatible with extramammary Paget disease of the vulva. Associated neoplastic conditions were excluded. Due to multiple relapses, the patient was submitted to three surgical interventions, including a total vulvectomy, and to external radiotherapy. The present case illustrates the chronic and recurrent nature of extramammary Paget disease despite aggressive procedures as well as the challenge in obtaining tumor-free resection margins.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Vulvar Neoplasms / Paget Disease, Extramammary / Vulvectomy / Imiquimod / Neoplasm Recurrence, Local / Antineoplastic Agents Limits: Aged / Female / Humans Language: English Journal: Rev. bras. ginecol. obstet Journal subject: Gynecology / Obstetrics Year: 2019 Type: Article Affiliation country: Portugal Institution/Affiliation country: Hospital de Santa Maria/PT

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Full text: Available Index: LILACS (Americas) Main subject: Vulvar Neoplasms / Paget Disease, Extramammary / Vulvectomy / Imiquimod / Neoplasm Recurrence, Local / Antineoplastic Agents Limits: Aged / Female / Humans Language: English Journal: Rev. bras. ginecol. obstet Journal subject: Gynecology / Obstetrics Year: 2019 Type: Article Affiliation country: Portugal Institution/Affiliation country: Hospital de Santa Maria/PT