Functional Features of Hemocoagulation in rats with Experimentally formed Arterial Hypertension in Conditions of Increased Motor Activity
Prensa méd. argent
;
105(8): 469-476, sept 2019. tab
Article
in English
| LILACS, BINACIS
| ID: biblio-1023268
ABSTRACT
In rats with experimentally formed arterial hypertension, lipid perxidation in the plasma, amplification of blood chotting mechanisms with a decrease in anticoagulation and fibrinolysis was noted. Regular forced jogging provided the experimental rats with a positive dynamic of all the indicators considered. Thus, with increased muscular activity, the level of acyl hydro-peroxides of plasma decreased in rats with arterial hypertension formed due to the enhancement of its antioxidant activity. In addition, with the increase in muscle activity in experimental rats, normalization of clotting factor activity, indices of general coagulation tests, antithrobin III activity and protein C was achieved. This was accompanied by a normalization of the level of plasminogen, a2-antiplasmin and spontaneous euglobulin lysis time. In rats with formed arterial hipertension with stgandard physical activity, the initial violations of the measured parameters were completely preserved (AU)
Index:
LILACS (Americas)
Main subject:
Blood Coagulation
/
Animal Experimentation
/
Hemostasis
/
Homeostasis
/
Hypertension
/
Motor Activity
Limits:
Animals
Language:
English
Journal:
Prensa méd. argent
Journal subject:
Medicine
Year:
2019
Type:
Article
Affiliation country:
RUSSIA
Institution/Affiliation country:
Kursk State Medical University/RU
/
Samara National Research University/RU
/
Samara National Research Univesity/RU
/
South-West State University/RU
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