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Susceptibility of Streptococcus agalactiae to erythromycin and clindamycin in pregnant women in the prenatal screening
Araújo, Max Roberto Batista; Reis, Poliane Vieira dos; Bicalho, Patrícia Helena do Nascimento; Seabra, Luisa Ferreira.
  • Araújo, Max Roberto Batista; Instituto Hermes Pardini. Setor de Microbiologia. Núcleo Técnico Operacional. Vespasiano. BR
  • Reis, Poliane Vieira dos; Instituto Hermes Pardini. Setor de Microbiologia. Núcleo Técnico Operacional. Vespasiano. BR
  • Bicalho, Patrícia Helena do Nascimento; Instituto Hermes Pardini. Setor de Microbiologia. Núcleo Técnico Operacional. Vespasiano. BR
  • Seabra, Luisa Ferreira; Instituto Hermes Pardini. Setor de Microbiologia. Núcleo Técnico Operacional. Vespasiano. BR
Clin. biomed. res ; 38(4): 311-315, 2018.
Article in English | LILACS | ID: biblio-1023693
ABSTRACT

Introduction:

Group B streptococcus (GBS), or Streptococcus agalactiae, is a bacterium found in normal human microbiota. However, it may cause neonatal pneumonia, sepsis, and meningitis. Genital colonization in pregnant women is associated with a higher risk of preterm birth. The treatment of choice is antibiotic therapy with beta-lactams, but in the case of multidrug-resistance, erythromycin and clindamycin can be used.

Methods:

This study evaluated bacterial cultures in the period from 2014 to 2015 from a group of 29,875 pregnant women. GBS colonization and resistance to erythromycin and clindamycin were investigated.

Results:

Positive cultures were found in 26.8% and 26.1% of the samples in 2014 and 2015, respectively. Levels of resistance to erythromycin and clindamycin were, respectively, 2.4% and 5.5% in 2014 and 3.2% and 6.5% in 2015.

Conclusion:

The investigation of GBS colonization and the evaluation of GBS resistance to erythromycin and clindamycin are of extreme relevance, given the increasing incidence of bacterial resistance, risks of preterm birth. (AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Streptococcus agalactiae / Drug Resistance, Microbial Type of study: Diagnostic study / Screening study Limits: Female / Humans / Pregnancy Language: English Journal: Clin. biomed. res Journal subject: Medicine Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Instituto Hermes Pardini/BR

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Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Streptococcus agalactiae / Drug Resistance, Microbial Type of study: Diagnostic study / Screening study Limits: Female / Humans / Pregnancy Language: English Journal: Clin. biomed. res Journal subject: Medicine Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Instituto Hermes Pardini/BR