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Draft genomes and reference transcriptomes extend the coding potential of the fish pathogen Piscirickettsia salmonis
Millar, Angela D; Tapia, Paz; Gómez, Fernando A; Marshall, Sergio H; Fuentes, Derie E; Valdes, Jorge H.
  • Millar, Angela D; Fraunhofer Chile Research Foundation. Aquaculture and Marine Ecosystems Division. Santiago. CL
  • Tapia, Paz; Fraunhofer Chile Research. Biocomputing and Applied Genetics Division. Santiago. CL
  • Gómez, Fernando A; Pontificia Universidad Católica de Valparaíso. Facultad de Ciencias. Instituto de Biología. Valparaíso. CL
  • Marshall, Sergio H; Pontificia Universidad Católica de Valparaíso. Facultad de Ciencias. Instituto de Biología. Valparaíso. CL
  • Fuentes, Derie E; Fraunhofer Chile Research Foundation. Aquaculture and Marine Ecosystems Division. Santiago. CL
  • Valdes, Jorge H; Fraunhofer Chile Research. Biocomputing and Applied Genetics Division. Santiago. CL
Electron. j. biotechnol ; 33: 36-38, May. 2018. tab
Article in English | LILACS | ID: biblio-1024852
ABSTRACT

Background:

Draft and complete genome sequences from bacteria are key tools to understand genetic determinants involved in pathogenesis in several disease models. Piscirickettsia salmonis is a Gram-negative bacterium responsible for the Salmon Rickettsial Syndrome (SRS), a bacterial disease that threatens the sustainability of the Chilean salmon industry. In previous reports, complete and draft genome sequences have been generated and annotated. However, the lack of transcriptome data underestimates the genetic potential, does not provide information about transcriptional units and contributes to disseminate annotation errors.

Results:

Here we present the draft genome and transcriptome sequences of four P. salmonis strains. We have identified the transcriptional architecture of previously characterized virulence factors and trait-specific genes associated to cation uptake, metal efflux, antibiotic resistance, secretion systems and other virulence factors.

Conclusions:

This data has provided a refined genome annotation and also new insights on the transcriptional structures and coding potential of this fish pathogen.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Salmonidae / Piscirickettsiaceae Infections / Piscirickettsia / Fish Diseases Type of study: Prognostic study Limits: Animals Language: English Journal: Electron. j. biotechnol Journal subject: Biotechnology Year: 2018 Type: Article Affiliation country: Chile Institution/Affiliation country: Fraunhofer Chile Research Foundation/CL / Fraunhofer Chile Research/CL / Pontificia Universidad Católica de Valparaíso/CL

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Full text: Available Index: LILACS (Americas) Main subject: Salmonidae / Piscirickettsiaceae Infections / Piscirickettsia / Fish Diseases Type of study: Prognostic study Limits: Animals Language: English Journal: Electron. j. biotechnol Journal subject: Biotechnology Year: 2018 Type: Article Affiliation country: Chile Institution/Affiliation country: Fraunhofer Chile Research Foundation/CL / Fraunhofer Chile Research/CL / Pontificia Universidad Católica de Valparaíso/CL