Use of cyanoacrylate-based surgical adhesives associated to the macroporous tape in skin synthesis in rats
Acta cir. bras
;
34(7): e201900701, 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1038120
ABSTRACT
Abstract Purpose:
To compare the use of new cyanoacrylate surgical adhesive associated with macroporous tapes in cutaneous synthesis.Methods:
Male Wistar rats with a longitudinal incision of 4cm were used on the back, divided into four groups GI used octyl-cyanoacrylate (Dermabond®), GII used N-2-butylcyanoacrylate, GIII used octyl-cyanoacrylate and macroporous tape and GIV used N-2-butyl cyanoacrylate and macroporous tape. On the fourteenth day, the rats were submitted to euthanasia, were divided in two parts, and a layer of skin subcutaneous tissue through an area of operative healing was removed. One part was submitted to the study of rupture strength with the use of tensiometer, and in the other part histological examination was performed.Results:
No force test was similar between groups I and II, being different from groups III and IV (P <0.001), which were identical to each other (P> 0.05). The units were compared among the studied groups, and they were different with the use of macroporous tapes (P> 0.05).Conclusions:
The purpose of macroporous tapes is associated with CA adhesives in cutaneous tissues that provide more resistant scars. The use of a combination of macroporous tapes leads to complete re-epithelialization, without provoking foreign body reaction, has hemostatic properties and does not cause an absorptive reaction.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin
/
Surgical Wound Dehiscence
/
Tissue Adhesives
/
Wound Healing
/
Enbucrilate
Type of study:
Risk factors
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UFMS/BR
/
Universidade Federal do Mato Grosso do Sul/BR
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