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The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats
Ozdenkaya, Yasar; Olmuscelik, Oktay; Basim, Pelin; Saka, Burcu; Arslan, Naciye Cigdem.
  • Ozdenkaya, Yasar; Medipol University Medical Faculty. Department of General Surgery. Istanbul. TR
  • Olmuscelik, Oktay; Medipol University Medical Faculty,. Department of Internal Medicine. Istanbul. TR
  • Basim, Pelin; Medipol University Medical Faculty. Department of General Surgery. Istanbul. TR
  • Saka, Burcu; Medipol University Medical Faculty. Department of Pathology. Istanbul. TR
  • Arslan, Naciye Cigdem; Medipol University Medical Faculty. Department of General Surgery. Istanbul. TR
Acta cir. bras ; 34(8): e201900801, 2019. tab, graf
Article in English | LILACS | ID: biblio-1038129
ABSTRACT
Abstract Purpose To evaluate the effect of fibrin glue on staple-line leak after sleeve gastrectomy. Methods Fourteen adult wistar rats 300 gr were randomized into two groups Control group (n=7) and study group (n=7). All the rats underwent sleeve gastrectomy using lineer stapler. In the study group, fibrin glue was used to reinforce the staple-line. The rats were sacrificed 7 days after surgery. The stomach was resected, submerged in saline and exposed to excess pressure to obtain a burst pressure value. The gastric staple line was evaluated histopathologically according to the Ehrlich Hunt scale. The results of the two groups were compared. Results The mean Ehrlich-Hunt scores for inflammation, fibroblastic activity and neo-angiogenesis were similar between the groups (p>0.05). Collagen deposition was significantly higher in study group (3.42±0.53) when compared with control group (2.57±0.78) (p=0.035). The mean burst pressure was 137.8±8.5 mmHg for control group and 135.0±8.1 mmHg for study group (p=0.536). Conclusion Reinforcement of the staple-line with fibrin glue has no effect on the burst pressure after sleeve gastrectomy. More studies are needed to evaluate the precautions against leak after sleeve gastrectomy.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Surgical Wound Dehiscence / Fibrin Tissue Adhesive / Surgical Stapling / Gastrectomy Type of study: Prognostic study Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Medipol University Medical Faculty/TR / Medipol University Medical Faculty,/TR

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Full text: Available Index: LILACS (Americas) Main subject: Surgical Wound Dehiscence / Fibrin Tissue Adhesive / Surgical Stapling / Gastrectomy Type of study: Prognostic study Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Medipol University Medical Faculty/TR / Medipol University Medical Faculty,/TR