Diphencyprone as a therapeutic option in cutaneous metastasis of melanoma. A single-institution experience
An. bras. dermatol
;
93(2): 299-301, Mar.-Apr. 2018. graf
Article
in English
| LILACS
| ID: biblio-1038267
ABSTRACT
Abstract Diphencyprone has been reported as a local immunotherapy for cutaneous melanoma metastases. We aim to report cases of melanoma patients treated with diphencyprone in a single Brazilian institution and highlight their outcomes. Since 2012, we have treated 16 melanoma patients with cutaneous metastases with topical diphencyprone. To date, we have had 37.5% of complete response, 25% of partial responses, and 31.25% patients without any response. Treatment was well tolerated and local toxicity was easily controlled. We believe topical diphencyprone is a feasible treatment that can be another option for treating melanoma patients, especially in cases of in-transit or extensive disease.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin Neoplasms
/
Cyclopropanes
/
Melanoma
/
Antineoplastic Agents
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
A.C. Camargo Cancer Center/BR
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