Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis
Braz. j. infect. dis
;
22(1): 51-54, Jan.-feb. 2018. tab, graf
Article
in English
| LILACS, SES-SP, SESSP-IDPCPROD, SES-SP
| ID: biblio-1039210
ABSTRACT
ABSTRACT A retrospective cohort study, were evaluated polymyxin B plus aminoglycosides or polymyxin B plus other antibiotics. Any degree of acute kidney injury occurred in 26 (86.6%) patients. The median time to acute kidney injury was 6.0 (95% CI 3-14) days in the polymyxin-aminoglycoside containing regimen group, against 27.0 (95% CI 6-42) days in the polymyxin with other antimicrobial combinations group (p = 0.03). Polymyxin B with aminoglycosides group progressed faster to any degree of renal dysfunction.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Polymyxin B
/
Enterobacteriaceae Infections
/
Kidney
/
Mediastinitis
/
Anti-Bacterial Agents
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Braz. j. infect. dis
Year:
2018
Type:
Article
Institution/Affiliation country:
Hospital de Clínicas de Porto Alegre/BR
/
Instituto Dante Pazzanese de Cardiologia/BR
/
The University of North Carolina at Chapel Hill/US
/
Universidade Federal de São Paulo/BR
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