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Epidemiological profile of patients with preterm premature rupture of membranes at a tertiary hospital in São Paulo, Brazil
Galletta, Marco Aurélio Knippel; Bittar, Roberto Eduardo; Agra, Isabela; Guerra, Eliane Cerqueira Leite; Francisco, Rossana Pulcineli Vieira; Zugaib, Marcelo.
  • Galletta, Marco Aurélio Knippel; Universidade de Sao Paulo. Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP. Sao Paulo. BR
  • Bittar, Roberto Eduardo; Universidade de Sao Paulo. Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP. Sao Paulo. BR
  • Agra, Isabela; Universidade de Sao Paulo. Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP. Sao Paulo. BR
  • Guerra, Eliane Cerqueira Leite; Universidade de Sao Paulo. Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP. Sao Paulo. BR
  • Francisco, Rossana Pulcineli Vieira; Universidade de Sao Paulo. Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP. Sao Paulo. BR
  • Zugaib, Marcelo; Universidade de Sao Paulo. Disciplina de Obstetricia, Departamento de Obstetricia e Ginecologia, Faculdade de Medicina FMUSP. Sao Paulo. BR
Clinics ; 74: e1231, 2019. tab, graf
Article in English | LILACS | ID: biblio-1039554
ABSTRACT

OBJECTIVE:

To perform a descriptive analysis of preterm premature rupture of membranes (PPROM) cases attended in a tertiary hospital.

METHOD:

Retrospective analysis of medical records and laboratory tests of patients admitted to a Brazilian tertiary hospital between 2006 and 2011, with a confirmed diagnosis of PPROM and gestational age (GA) at delivery <37 weeks.

RESULTS:

A total of 299 pregnant women were included in the study. Nine patients evolved to abortion, and 290 pregnant women remained for the final analysis. There was initial diagnostic doubt in 17.6% of the cases. The oligohydramnios rate [amniotic fluid index (AFI) <5] was 27.9% on admission. Chorioamnionitis was initially diagnosed in 10.8% of the patients and was retrospectively confirmed in 22.9% of the samples. The latency period had a mean of 9.1 days. The main reasons for interruption were premature labor (55.2%), GA ≥36 weeks (27.2%), and fetal distress (6.9%). The delivery method was cesarean section in 55% of cases. The mean birth weight was 2,124 grams, and 67% of the neonates had a low birth weight (<2500 g). The GA at delivery averaged 33.5 weeks. The stillbirth rate was 5.3%, and the early neonatal mortality rate was 5.6%. There were complications at delivery in 18% of mothers.

CONCLUSION:

In one of the few Brazilian reports on the epidemiological profile of PPROM, with GA until 37 weeks and intercurrences generally excluded from assessments (such as twinning and fetal malformations), there is a favorable evolution, with an acceptable rate of complications.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Fetal Membranes, Premature Rupture Type of study: Observational study / Risk factors Limits: Adolescent / Adult / Female / Humans / Infant / Infant, Newborn Country/Region as subject: South America / Brazil Language: English Journal: Clinics Journal subject: Medicine Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de Sao Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Fetal Membranes, Premature Rupture Type of study: Observational study / Risk factors Limits: Adolescent / Adult / Female / Humans / Infant / Infant, Newborn Country/Region as subject: South America / Brazil Language: English Journal: Clinics Journal subject: Medicine Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de Sao Paulo/BR