Incidence and spatial distribution of Chronic Myeloid Leukemia by regions of economic development in the state of Pernambuco, Brazil
Hematol., Transfus. Cell Ther. (Impr.)
;
41(3): 212-215, July-Sept. 2019. tab, mapas
Article
in English
| LILACS
| ID: biblio-1039920
ABSTRACT
ABSTRACT Background:
The establishment of regional development poles in the State of Pernambuco, Brazil was characterized by industrial expansion and consequent concerns about the increase in the occurrence of diseases, specifically those having long latency periods, as is the case of Chronic Myeloid Leukemia.Methods:
The study included 367 patients diagnosed with Chronic Myeloid Leukemia over a ten-year period at a reference treatment center. Records of patient charts and the TerraView software were used, respectively, for data collection and geographic mapping of the cases from the twelve established State development regions.Results:
A total incidence of 3.4 cases per 100,000 inhabitants was found, with a predominance of the disease among males, a median age of 47 years, a mestizo ethnicity, with elementary schooling and residence in urban area. Microregional incidence varied, but there was no significant variation in numbers over the years, and no relevant socio-environmental determinants were identified.Conclusion:
The present study determined the incidence and characterized the spatial distribution of Chronic Myeloid Leukemia cases over a decade in a northeastern Brazilian state. The variation in the incidence rate by region of development is compatible with a homogeneous distribution of the cases. The work is a baseline study to be used for present and future analyses of the impact of the state economic development poles and the occurrence of this chronic malignant disease.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
/
Epidemiology
/
Incidence
/
Geographic Mapping
Type of study:
Health economic evaluation
/
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Hematol., Transfus. Cell Ther. (Impr.)
Journal subject:
Hematologia
/
TransfusÆo de Sangue
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro de Pesquisas Aggeu Magalhães/BR
/
Fundação Hemope/BR
/
Universidade Federal de Pernambuco - UFPE/BR
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