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A comparison of the sealing abilities between Biodentine and MTA as root-end filling materials and their effects on bone healing in dogs after periradicular surgery
Tang, Jing-jing; Shen, Zong-shan; Qin, Wei; Lin, Zhengmei.
  • Tang, Jing-jing; Sun Yat-sen University. Guanghua School of Stomatology. Department of Operative Dentistry and Endodontics. Guangzhou. CN
  • Shen, Zong-shan; Sun Yat-sen University. Guanghua School of Stomatology. Department of Operative Dentistry and Endodontics. Guangzhou. CN
  • Qin, Wei; Sun Yat-sen University. Guanghua School of Stomatology. Department of Operative Dentistry and Endodontics. Guangzhou. CN
  • Lin, Zhengmei; Sun Yat-sen University. Guanghua School of Stomatology. Department of Operative Dentistry and Endodontics. Guangzhou. CN
J. appl. oral sci ; 27: e20180693, 2019. graf
Article in English | LILACS, BBO | ID: biblio-1040226
ABSTRACT
ABSTRACT

Objectives:

To compare the sealing ability and biocompatibility of Biodentine with mineral trioxide aggregate (MTA) when used as root-end filling materials.

Methodology:

The Cell Counting Kit-8 (CCK-8) assay was used to compare the cytotoxicity of MTA and Biodentine. Twenty-one extracted teeth with a single canal were immersed in an acidic silver nitrate solution after root-end filling. Then, the volume and depth of silver nitrate that infiltrated the apical portion of the teeth were analyzed using micro-computed tomography (micro-CT). Seventy-two roots from 3 female beagle dogs were randomly distributed into 3 groups and apical surgery was performed. After six months, the volume of the bone defect surrounding these roots was analyzed using micro-CT.

Results:

Based on the results of the CCK-8 assay, MTA and Biodentine did not show statistically significant differences in cytotoxicity (P>0.05). The volume and the depth of the infiltrated nitrate solution were greater in the MTA group than in the Biodentine group (P<0.05). The volume of the bone defect was larger in the MTA group than in the Biodentine group. However, the difference was not significant (P>0.05). The volumes of the bone defects in the MTA and Biodentine groups were smaller than the group without any filling materials (P<0.05).

Conclusions:

MTA and Biodentine exhibited comparable cellular biocompatibility. Biodentine showed a superior sealing ability to MTA in root-end filling. Both Biodentine and MTA promoted periradicular bone healing in beagle dog periradicular surgery models.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Oxides / Periapical Tissue / Periodontal Ligament / Root Canal Filling Materials / Root Canal Therapy / Wound Healing / Silicates / Calcium Compounds / Aluminum Compounds Type of study: Prognostic study Limits: Animals / Humans / Male Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2019 Type: Article Affiliation country: China Institution/Affiliation country: Sun Yat-sen University/CN

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Full text: Available Index: LILACS (Americas) Main subject: Oxides / Periapical Tissue / Periodontal Ligament / Root Canal Filling Materials / Root Canal Therapy / Wound Healing / Silicates / Calcium Compounds / Aluminum Compounds Type of study: Prognostic study Limits: Animals / Humans / Male Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2019 Type: Article Affiliation country: China Institution/Affiliation country: Sun Yat-sen University/CN