The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study
J. appl. oral sci
;
27: e20180779, 2019. tab, graf
Article
in English
| LILACS, BBO
| ID: biblio-1040232
ABSTRACT
Abstract Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients. Objective:
To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle.Methodology:
Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using twomethods:
1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey's post hoc test were used in the statistical analyses.Results:
Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness.Conclusion:
PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Acrylic Resins
/
Candida albicans
/
Polymethyl Methacrylate
/
Denture Bases
/
Nanodiamonds
Type of study:
Evaluation studies
Limits:
Humans
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2019
Type:
Article
Affiliation country:
Finland
/
Saudi Arabia
Institution/Affiliation country:
Imam Abdulrahman Bin Faisal University/SA
/
University of Oulu/FI
/
University of Turku/FI
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