Your browser doesn't support javascript.
loading
The effect of nanodiamonds on candida albicans adhesion and surface characteristics of PMMA denture base material - an in vitro study
Fouda, Shaimaa M; Gad, Mohammed M; Ellakany, Passent; Al-Thobity, Ahmad M; Al-Harbi, Fahad A; Virtanen, Jorma I; Raustia, Aune.
  • Fouda, Shaimaa M; Imam Abdulrahman Bin Faisal University. College of Dentistry. Department of Substitutive Dental Sciences. Dammam. SA
  • Gad, Mohammed M; Imam Abdulrahman Bin Faisal University. College of Dentistry. Department of Substitutive Dental Sciences. Dammam. SA
  • Ellakany, Passent; Imam Abdulrahman Bin Faisal University. College of Dentistry. Department of Substitutive Dental Sciences. Dammam. SA
  • Al-Thobity, Ahmad M; Imam Abdulrahman Bin Faisal University. College of Dentistry. Department of Substitutive Dental Sciences. Dammam. SA
  • Al-Harbi, Fahad A; Imam Abdulrahman Bin Faisal University. College of Dentistry. Department of Substitutive Dental Sciences. Dammam. SA
  • Virtanen, Jorma I; University of Turku. Faculty of Medicine. Department of Community Dentistry. Turku. FI
  • Raustia, Aune; University of Oulu. Faculty of Medicine. Research Unit of Oral Health Sciences, Prosthetic Dentistry and Stomatognathic Physiology. Oulu. FI
J. appl. oral sci ; 27: e20180779, 2019. tab, graf
Article in English | LILACS, BBO | ID: biblio-1040232
ABSTRACT
Abstract Candida albicans is the main causative pathogen of denture stomatitis, which affects many complete denture patients.

Objective:

To evaluate the effect of different concentrations of nanodiamonds (NDs) added to polymethyl methacrylate (PMMA) denture base material on Candida albicans adhesion as well as on surface roughness and contact angle.

Methodology:

Acrylic resin specimens sized 10×10×3 mm3 were prepared and divided into four groups (n=30) according to ND concentration (0%, 0.5%, 1%, 1.5% by wt). Surface roughness was measured with a profilometer, and the contact angle with a goniometer. The effect of NDs on Candida albicans adhesion was evaluated using two

methods:

1) slide count and 2) direct culture test. Analysis of variance (ANOVA) and Tukey's post hoc test were used in the statistical analyses.

Results:

Addition of NDs decreased the Candida albicans count significantly more than in the control group (p<0.05), with a lowest of 1% NDs. Addition of NDs also significantly decreased the surface roughness (p<0.05), but the contact angle remained the same. Incorporation of NDs into the PMMA denture base material effectively reduced Candida albicans adhesion and decreased surface roughness.

Conclusion:

PMMA/NDs composites could be valuable in the prevention of denture stomatitis, which is considered one of the most common clinical problems among removable denture wearers.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Acrylic Resins / Candida albicans / Polymethyl Methacrylate / Denture Bases / Nanodiamonds Type of study: Evaluation studies Limits: Humans Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2019 Type: Article Affiliation country: Finland / Saudi Arabia Institution/Affiliation country: Imam Abdulrahman Bin Faisal University/SA / University of Oulu/FI / University of Turku/FI

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Acrylic Resins / Candida albicans / Polymethyl Methacrylate / Denture Bases / Nanodiamonds Type of study: Evaluation studies Limits: Humans Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2019 Type: Article Affiliation country: Finland / Saudi Arabia Institution/Affiliation country: Imam Abdulrahman Bin Faisal University/SA / University of Oulu/FI / University of Turku/FI