Single shot of 17D vaccine may not confer life-long protection against yellow fever
Mem. Inst. Oswaldo Cruz
;
113(2): 135-137, Feb. 2018.
Article
in English
| LILACS
| ID: biblio-1040589
ABSTRACT
The yellow fever (YF) vaccine has been used since the 1930s to prevent YF, which is a severe infectious disease caused by the yellow fever virus (YFV), and mainly transmitted by Culicidae mosquitoes from the genera Aedes and Haemagogus . Until 2013, the World Health Organization (WHO) recommended the administration of a vaccine dose every ten years. A new recommendation of a single vaccine dose to confer life-long protection against YFV infection has since been established. Recent evidence published elsewhere suggests that at least a second dose is needed to fully protect against YF disease. Here, we discuss the feasibility of administering multiple doses, the necessity for a new and modern vaccine, and recommend that the WHO conveys a meeting to discuss YFV vaccination strategies for people living in or travelling to endemic areas.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Yellow Fever
/
Yellow fever virus
/
Immunization Schedule
/
Antibodies, Neutralizing
Limits:
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2018
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Evandro Chagas/BR
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