Human sapovirus GI. 2 and GI. 3 from children with acute gastroenteritis in northern Brazil
Mem. Inst. Oswaldo Cruz
;
114: e180574, 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1040626
ABSTRACT
Human sapoviruses (HSaV) are considered important causative agents of acute gastroenteritis in humans worldwide. However, knowledge of the genetic characteristics of the whole genome of HSaV in Brazil is limited. Here we report the complete genome sequences of six HSaVs GI.2 and two GI.3 strains obtained from children with acute gastroenteritis in the Northern region of Brazil. Next generation sequencing was used to obtain the full genome and molecular characterization of the genome was performed. Phylogenetic analysis of the genome was also performed. Only one complete HSaV GI.2 genome characterization in the country precedes that of the present study. This is the first complete genome sequence of genotype GI.3 in Brazil. The data obtained in this investigation can contribute to the augmentation of the database on the molecular diversity of HSaVs strains circulating in Brazil, and to the improvement of current typing protocols.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Caliciviridae Infections
/
Sapovirus
/
Gastroenteritis
Limits:
Child
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2019
Type:
Article
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Blood Systems Research Institute/US
/
Faculdade de Medicina do ABC/BR
/
Instituto Adolfo Lutz/BR
/
Laboratório Central de Saúde Pública do Tocantins/BR
/
Universidade Federal de Tocantins/BR
/
Universidade Federal do Pará/BR
/
Universidade de São Paulo/BR
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