Clonal relation and antimicrobial resistance pattern of extended-spectrum ß-lactamase- and AmpC ß-lactamase-producing Enterobacter spp. isolated from different clinical samples in Tehran, Iran
Rev. Soc. Bras. Med. Trop
;
51(1): 88-93, Jan.-Feb. 2018. tab
Article
in English
| LILACS
| ID: biblio-1041448
ABSTRACT
Abstract INTRODUCTION:
Here, we determined the genes encoding antibiotic resistance enzymes and virulence factors and evaluated the genetic relationship between Enterobacter spp. isolated from different clinical samples.METHODS:
A total of 57 clinical isolates of Enterobacter spp. were tested for the production of extended-spectrum β-lactamases (ESBLs), carbapenemase, and AmpC using phenotypic and genotypic methods.RESULTS:
The most common ESBLs and AmpC β-lactamases were bla TEM (63.3%) and bla EBC (57.7%), respectively. The most prevalent virulence gene was rpos (87.7%). The random amplified polymorphic DNA (RAPD) patterns of strains were genetically unrelated.CONCLUSIONS:
RAPD polymerase chain reaction analysis revealed high genetic diversity among isolates.
Full text:
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Index:
LILACS (Americas)
Main subject:
Bacterial Proteins
/
Beta-Lactamases
/
Escherichia coli
/
Feces
/
Anti-Bacterial Agents
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2018
Type:
Article
Affiliation country:
Iran
Institution/Affiliation country:
Kerman University of Medical Sciences/IR
/
Tehran University of Medical Sciences/IR
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