Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report
Rev. Soc. Bras. Med. Trop
;
51(2): 231-233, Mar.-Apr. 2018. tab
Article
in English
| LILACS
| ID: biblio-1041452
ABSTRACT
Abstract INTRODUCTION:
The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. METHODS In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. RESULTS Fas2-ELISA demonstrated negative results in all HCC patients included in this study. CONCLUSIONS The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Immunoglobulin G
/
Antibodies, Helminth
/
Carcinoma, Hepatocellular
/
Fasciola hepatica
/
Fascioliasis
/
Liver Neoplasms
Type of study:
Diagnostic study
/
Etiology study
Limits:
Aged80
/
Animals
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Peru
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2018
Type:
Article
Affiliation country:
France
/
Peru
/
United States
Institution/Affiliation country:
Instituto Nacional de Enfermedades Neoplásicas/PE
/
Stony Brook University/US
/
Universidad Peruana Cayetano Heredia/PE
/
Université de Toulouse/FR
Similar
MEDLINE
...
LILACS
LIS