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Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
Gomes, Luciano Teixeira; Bellei, Ananda Karla; Andrade, Denise Inácio de; Gotardo, Priscila Zanini; Nery, Andreia Ferreira; Fontes, Cor Jesus Fernandes.
  • Gomes, Luciano Teixeira; Universidade Federal de Mato Grosso. Hospital Universitário Júlio Muller/EBSERH. Núcleo de Estudos em Doenças Infecciosas e Parasitárias. Cuiabá. BR
  • Bellei, Ananda Karla; Faculdade de Ciências Biomédicas de Cacoal. Curso de Graduação em Medicina. Cacoal. BR
  • Andrade, Denise Inácio de; Faculdade de Ciências Biomédicas de Cacoal. Curso de Graduação em Medicina. Cacoal. BR
  • Gotardo, Priscila Zanini; Faculdade de Ciências Biomédicas de Cacoal. Curso de Graduação em Medicina. Cacoal. BR
  • Nery, Andreia Ferreira; Universidade Federal de Mato Grosso. Hospital Universitário Júlio Muller/EBSERH. Núcleo de Estudos em Doenças Infecciosas e Parasitárias. Cuiabá. BR
  • Fontes, Cor Jesus Fernandes; Universidade Federal de Mato Grosso. Hospital Universitário Júlio Muller/EBSERH. Núcleo de Estudos em Doenças Infecciosas e Parasitárias. Cuiabá. BR
Rev. Soc. Bras. Med. Trop ; 52: e20170412, 2019. tab, graf
Article in English | LILACS | ID: biblio-1041539
ABSTRACT
Abstract INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process.

METHODS:

We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax.

RESULTS:

Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001).

CONCLUSIONS:

Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.
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Full text: Available Index: LILACS (Americas) Main subject: Uric Acid / Malaria, Vivax / Antimalarials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Faculdade de Ciências Biomédicas de Cacoal/BR / Universidade Federal de Mato Grosso/BR

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Full text: Available Index: LILACS (Americas) Main subject: Uric Acid / Malaria, Vivax / Antimalarials Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Faculdade de Ciências Biomédicas de Cacoal/BR / Universidade Federal de Mato Grosso/BR