Genotypes of clinical varicella-zoster virus isolates from Manaus, Brazil
Rev. Soc. Bras. Med. Trop
;
52: e20180166, 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1041564
ABSTRACT
Abstract INTRODUCTION:
Vaccination against varicella-zoster virus (VZV) has been effective and safe in countries that routinely administer the vaccine. Brazil began universal VZV vaccination in 2013. This study aimed to identify VZV genotypes present in Manaus, Brazil prior to widespread immunization.METHODS:
Vesicular lesions or cerebral-spinal-fluid samples were collected from patients diagnosed with VZV, herpes zoster, or meningitis/encephalitis. DNA was extracted, amplified, and sequenced.RESULTS:
Half the isolates were clade-5 viruses and the remaining were divided between the European clades 1 and 3.CONCLUSIONS:
This study provides insights into the circulating VZV genotypes in Manaus prior to widespread vaccination.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Herpesvirus 3, Human
/
Varicella Zoster Virus Infection
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2019
Type:
Article
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Centers for Disease Control and Prevention/US
/
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado/BR
/
Hospital Universitário Getúlio Vargas/BR
/
Universidade do Estado do Amazonas/BR
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