Brazilian spotted fever prevention through a nonlethal capybara population control strategy
Rev. Soc. Bras. Med. Trop
;
52: e20190156, 2019. graf
Article
in English
| LILACS
| ID: biblio-1041580
ABSTRACT
Abstract INTRODUCTION:
Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.METHODS:
We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine.RESULTS:
The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas.CONCLUSIONS:
We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Rodentia
/
Rocky Mountain Spotted Fever
/
Gonadotropin-Releasing Hormone
/
Contraception, Immunologic
/
Vaccines, Contraceptive
Limits:
Animals
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade de São Paulo/BR
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