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Chemical constituents from ethanol extract of Polyalthia rumphii branches and their cytotoxicity evaluation
Wang, Tianshan; Wu, Xiaopeng; Liu, Yanping; Luo, Youping; Li, Xiang; Zhou, Yujie; Yang, AiPing; Yan, Zhengmeng; Ye, Ling; Chen, Siwei; Fu, Jinshuai; Jiao, Xianzhi.
  • Wang, Tianshan; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Wu, Xiaopeng; Chinese Academy of Tropical Agricultural Science. Institute of Tropical Bioscience and Biotechnology. Haikou. CN
  • Liu, Yanping; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Luo, Youping; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Li, Xiang; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Zhou, Yujie; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Yang, AiPing; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Yan, Zhengmeng; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Ye, Ling; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Chen, Siwei; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Fu, Jinshuai; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
  • Jiao, Xianzhi; Hainan Normal University. College of Chemistry and Chemical Engineering. Haikou. CN
Rev. bras. farmacogn ; 28(2): 235-238, Mar.-Apr. 2018. tab, graf
Article in English | LILACS | ID: biblio-1042261
ABSTRACT
ABSTRACT Twelve known compounds, including eight alkaloids, three lignans and one gossypol derivative, were isolated from the branches of Polyalthia rumphii (Blume ex Hensch.) Merr., Annonaceae. The chemical structures were determined by spectroscopic methods and comparison with literature data. All the isolates were evaluated the cytotoxicity against three human cancer cell lines: Hela, MCF-7 and A549, the results showed that partial of isolates displayed weak cytotoxicities with the IC50 values ranging from 25 to 40 µg/ml.

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Full text: Available Index: LILACS (Americas) Language: English Journal: Rev. bras. farmacogn Journal subject: Pharmacy Year: 2018 Type: Article Affiliation country: China Institution/Affiliation country: Chinese Academy of Tropical Agricultural Science/CN / Hainan Normal University/CN

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Full text: Available Index: LILACS (Americas) Language: English Journal: Rev. bras. farmacogn Journal subject: Pharmacy Year: 2018 Type: Article Affiliation country: China Institution/Affiliation country: Chinese Academy of Tropical Agricultural Science/CN / Hainan Normal University/CN