Comment about "Randomized cross-over clinical trial comparing two pharmacokinetic models of propofol using entropy indices" / Comentario acerca de «Ensayo clínico cruzado y aleatorizado para comparar 2 modelos farmacocinéticos de propofol usando índices de entropía¼

ABSTRACT

The article, "Clinical cross-section, randomized clinical trial comparing two pharmacokinetic propofol models using entropy indexes",1 published in the July-September 2016 journal, although an interesting and novel idea, it seems to me that a big mistake was made in the study's clinical design, that totally invalidates the results.

RESUMEN

El artículo, "Clinical cross-section, randomized clinical trial comparing two pharmacokinetic propofol models using entropy indexes",1 publicado en la revista de julio-septiembre de 2016, aunque es una idea interesante y novedosa, me parece que se cometió un gran error en el diseño clínico del estudio, que invalida totalmente los resultados.