Incidence rates and temporal trends of cervical cancer relating to opportunistic screening in two developed metropolitan regions of Brazil: a population-based cohort study
São Paulo med. j
;
137(4): 322-328, July-Aug. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1043438
ABSTRACT
ABSTRACT BACKGROUND:
Brazilian opportunistic screening programs for cervical cancer have limited impact. In the regions of two cities (Campinas and Curitiba) with high human development indices, consistent information from 96-97% of all cervical cancer cases managed within the public healthcare system is available.OBJECTIVE:
To estimate the incidence rate (IR) and temporal trends in these regions, covering 2001-2012. DESIGN ANDSETTING:
A population-based cohort study was conducted under the assumption that all cervical cancer cases were managed in cancer referral center hospitals.METHODS:
3,364 records (1,646 from Campinas; 1,718 from Curitiba) were analyzed to provide estimates of IR, age-standardized IR (ASR) and cervical cancer trends (shown per 100,000 women/year). Longitudinal patterns were analyzed using linear regression and shown as annual percentage change (APC); P < 0.05 for significance.RESULTS:
Annual IR and ASR estimates for cervical cancer ranged from 3.8 to 8.0 over 2001-2012, decreasing over more recent years, and were similar for the two regions. The age-specific IR was about 50% lower among women aged 45 years or older (IR-2001/IR-2012 Campinas = 14.8/8.0; Curitiba = 18.7/8.3; P < 0.001). There was an increasing APC trend in Campinas among women aged 15-24 years, and a decreasing IR trend for squamous-cell histology in both regions (P < 0.05).CONCLUSION:
Cervical cancer incidence estimates showed slowly decreasing trends in both regions, most evidently for women aged 45 years or older and for squamous-cell histology. These findings reflect the opportunistic nature of the population screening program, despite the comparatively high economic development level in the two regions.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Uterine Cervical Neoplasms
/
Early Detection of Cancer
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital Erasto Gaertner/BR
/
Universidade Estadual de Campinas/BR
/
Universidade Federal do Paraná/BR
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