In vitro screening for acetylcholinesterase and butyrylcholinesterase inhibition and antimicrobial activity of chia seeds (Salvia hispanica)
Electron. j. biotechnol
;
37: 1-10, Jan. 2019. tab, graf, ilus
Article
in English
| LILACS
| ID: biblio-1048922
ABSTRACT
BACKGROUND:
Chia seeds are gaining increasing interest among food producers and consumers because of their prohealth properties.RESULTS:
The aim of this work was to evaluate the potential of chia seeds to act as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors. The highest inhibitory activity against AChE and BChE was observed for colored seed ethanol extracts. A positive correlation was found between the presence of quercetin and isoquercetin as well as protocatechuic, hydroxybenzoic, and coumaric acids and the activity of extracts as AChE and BChE inhibitors. It has also been shown that grain fragmentation affects the increase in the activity of seeds against cholinesterases (ChE). Furthermore, seeds have been shown to be a source of substances that inhibit microbial growth.CONCLUSIONS:
It was found that the chia seed extracts are rich in polyphenols and inhibit the activity of ChEs; therefore, their use can be considered in further research in the field of treatment and prevention of neurodegenerative diseases.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Seeds
/
Butyrylcholinesterase
/
Cholinesterase Inhibitors
/
Salvia
/
Anti-Infective Agents
Type of study:
Diagnostic study
/
Screening study
Language:
English
Journal:
Electron. j. biotechnol
Journal subject:
Biotechnology
Year:
2019
Type:
Article
Affiliation country:
Poland
Institution/Affiliation country:
Poznan University of Life Sciences/PL
/
Poznan University of Medical Sciences/PL
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