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Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease
Kollabathula, Arpitha; Vishwajeet, Vikarn; Gupta, Kirti; Mitra, Suvradeep; Sharma, Vibhav; Ray, Pallab; Bhalla, Ashish.
  • Kollabathula, Arpitha; Postgraduate Institute of Medical Education and Research. Department of Histopathology. Chandigarh. IN
  • Vishwajeet, Vikarn; Postgraduate Institute of Medical Education and Research. Department of Histopathology. Chandigarh. IN
  • Gupta, Kirti; Postgraduate Institute of Medical Education and Research. Department of Histopathology. Chandigarh. IN
  • Mitra, Suvradeep; Postgraduate Institute of Medical Education and Research. Department of Histopathology. Chandigarh. IN
  • Sharma, Vibhav; Postgraduate Institute of Medical Education and Research. Department of Internal Medicine. Chandigarh. IN
  • Ray, Pallab; Postgraduate Institute of Medical Education and Research. Department of Medical Microbiology. Chandigarh. IN
  • Bhalla, Ashish; Postgraduate Institute of Medical Education and Research. Department of Internal Medicine. Chandigarh. IN
Autops. Case Rep ; 10(1): 2019128, Jan.-Mar. 2020. ilus, tab
Article in English | LILACS | ID: biblio-1052960
ABSTRACT
We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium. The autopsy revealed multiple tumor-like masses in the liver, which on histological examination depicted multiple large suppurative granulomas with the presence of variable acid-fast coccobacilli (consistent with Brucella spp.). Interestingly, extensive amyloid deposition in multiple organs was noted. To the best of our knowledge, this is the first case of chronic brucellosis causing tumor-like abscesses in the liver accompanied by secondary systemic amyloidosis in a patient with underlying autosomal dominant polycystic kidney disease.
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Full text: Available Index: LILACS (Americas) Main subject: Polycystic Kidney, Autosomal Dominant / Amyloidosis Type of study: Diagnostic study Limits: Humans / Male Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2020 Type: Article Affiliation country: India Institution/Affiliation country: Postgraduate Institute of Medical Education and Research/IN

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Full text: Available Index: LILACS (Americas) Main subject: Polycystic Kidney, Autosomal Dominant / Amyloidosis Type of study: Diagnostic study Limits: Humans / Male Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2020 Type: Article Affiliation country: India Institution/Affiliation country: Postgraduate Institute of Medical Education and Research/IN