Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
42(1): 63-67, Jan.-Feb. 2020. tab
Article
in English
| LILACS
| ID: biblio-1055364
ABSTRACT
Objective:
To determine whether people with a Sardinian genetic background who live in the megacities of South America have a higher frequency of hypomania than residents of Sardinia.Methods:
A community survey of Sardinian immigrants was carried out in four Brazilian metropoles (n=218) and Buenos Aires (n=306). The results were compared with those of a study involving a similar methodology (Mood Disorder Questionnaire [MDQ] as a screening tool) conducted in seven Italian regions, including a sub-sample from Sardinia.Results:
There was a higher prevalence of lifetime hypomania among Sardinians living in the Brazilian metropoles than among those living in Sardinia. This result was also consistent with Sardinian immigrants in Buenos Aires. After stratification by sex and age, the lifetime prevalence of MDQ scores ≥ 8 among Sardinians in South-American megacities and Sardinia was 8.6% vs. 2.9%, respectively (p < 0.0001).Conclusions:
The higher frequency of hypomania in migrant populations appears to favor an evolutionary view in which mood disorders may be a maladaptive aspect of a genetic background with adaptive characteristics.
Full text:
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Index:
LILACS (Americas)
Main subject:
Transients and Migrants
/
Bipolar Disorder
Type of study:
Etiology study
/
Prevalence study
/
Qualitative research
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Argentina
/
Brazil
/
Europa
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2020
Type:
Article
Affiliation country:
Argentina
/
Brazil
/
Italy
/
United States
Institution/Affiliation country:
Centro Lucio Bini Cagliari/IT
/
Columbia University/US
/
Universidad del Museo Social Argentino/AR
/
Universidade Federal do Rio de Janeiro (UFRJ)/BR
/
Università La Sapienza/IT
/
Università di Cagliari/IT
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