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Mesenchymal Stromal Cells Modulate PAF-stimulated Equine Alveolar Macrophages
Department of Animal ScienceMichelotto, Pedro Vicente; Department of Animal ScienceBastos, Fernanda Zettel; Department of Animal ScienceBarussi, Fernanda Cristina Mendes; Laboratory for Experimental Cell CultureSenegaglia, Alexandra Cristina; Nishiyama, Anita.
Affiliation
  • Department of Animal ScienceMichelotto, Pedro Vicente; Pontifical Catholic University. School of Life Sciences. Department of Animal ScienceMichelotto, Pedro Vicente. Curitiba. BR
  • Department of Animal ScienceBastos, Fernanda Zettel; Pontifical Catholic University. School of Life Sciences. Department of Animal ScienceBastos, Fernanda Zettel. Curitiba. BR
  • Department of Animal ScienceBarussi, Fernanda Cristina Mendes; Pontifical Catholic University. School of Life Sciences. Department of Animal ScienceBarussi, Fernanda Cristina Mendes. Curitiba. BR
  • Laboratory for Experimental Cell CultureSenegaglia, Alexandra Cristina; Pontifical Catholic University. School of Medicine. Laboratory for Experimental Cell CultureSenegaglia, Alexandra Cristina. Curitiba. BR
  • Nishiyama, Anita; Federal University of Paraná. Department of Physiology. Curitiba. BR
Braz. arch. biol. technol ; Braz. arch. biol. technol;62: e19180362, 2019. graf
Article in En | LILACS | ID: biblio-1055420
Responsible library: BR1.1
ABSTRACT
Abstract Platelet-activating factor (PAF) is a potent proinflammatory mediator that is produced in increased amounts in the lungs of asthmatic humans and horses. The present pilot study, shows that mesenchymal stromal cells can modulate alveolar macrophage function in asthma, interfering in the activity of PAF, being another potential pathway for mesenchymal stromal cells benefits in asthma.
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Full text: 1 Index: LILACS Main subject: Asthma / Platelet Activating Factor / Cell- and Tissue-Based Therapy / Horses Limits: Animals Language: En Journal: Braz. arch. biol. technol Journal subject: BIOLOGIA Year: 2019 Type: Article

Full text: 1 Index: LILACS Main subject: Asthma / Platelet Activating Factor / Cell- and Tissue-Based Therapy / Horses Limits: Animals Language: En Journal: Braz. arch. biol. technol Journal subject: BIOLOGIA Year: 2019 Type: Article