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Upper urinary tract stone compositions: the role of age and gender
Wang, Shu; Zhang, Yitian; Zhang, Xin; Tang, Yuzhe; Li, Jianxing.
  • Wang, Shu; Beijing Tsinghua Changgung Hospital. Department of Urology. Beijing. CN
  • Zhang, Yitian; University of North Carolina. Chapel Hill. US
  • Zhang, Xin; Beijing Tsinghua Changgung Hospital. Department of Urology. Beijing. CN
  • Tang, Yuzhe; Beijing Tsinghua Changgung Hospital. Department of Urology. Beijing. CN
  • Li, Jianxing; Beijing Tsinghua Changgung Hospital. Department of Urology. Beijing. CN
Int. braz. j. urol ; 46(1): 70-80, Jan.-Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1056356
ABSTRACT
ABSTRACT

Objective:

To analyze the compositions of upper urinary tract stones and investigate their distributions in different gender and age groups. Materials and

Methods:

Patients diagnosed with upper urinary tract stone disease between December 2014 and March 2018 were retrospectively reviewed. Patient's age, gender, BMI, comorbidities, stone event characteristics, and compositions were collected, and proportions of stone components in different gender and age groups were analyzed.

Results:

A total of 1532 stone analyses were performed (992 from males and 540 from females). The mean age was younger in males (p <0.001). Males included more cases with larger BMI, hyperuricemia, and obesity, while females had more urinary tract infections. Multiple components were present in 61.8% of stones. Calcium oxalate (CaOx) (67.0%) was the most common component, followed by uric acid (UA) (11.8%), infection stone (11.4%), calcium phosphate (CaP) (8.0%), cystine (1.1%), brushite (0.4%), and 2, 8-dihydroxyadenine (0.2%). Men contributed with more CaOx stones than women at age 30-49 years (all p <0.01) and more UA stones at 30-59 years (all p <0.05). Women contributed with more infection stones than men in age groups 30-49 and 60-69 years (all p <0.05), and more CaP stones at 30-49 years. The prevalence peak was 50-59 years in men and 60-69 years in women. Both genders had the lowest prevalence in adolescence. Prevalence of UA stones increased while that of infection stones decreased with aging in both genders.

Conclusions:

Age and sex had a strong association with distribution of stone compositions in this Chinese cohort.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Urinary Calculi / Risk Factors Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2020 Type: Article Affiliation country: China / United States Institution/Affiliation country: Beijing Tsinghua Changgung Hospital/CN / University of North Carolina/US

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Full text: Available Index: LILACS (Americas) Main subject: Urinary Calculi / Risk Factors Type of study: Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Int. braz. j. urol Journal subject: Urology Year: 2020 Type: Article Affiliation country: China / United States Institution/Affiliation country: Beijing Tsinghua Changgung Hospital/CN / University of North Carolina/US