Correlation of Low CD4+ Counts with High Dental Caries Prevalence in Children Living with Perinatal HIV/AIDS Undergoing Antiretroviral Therapy
Pesqui. bras. odontopediatria clín. integr
;
19: e4819, 2019. graf
Article
in English
| LILACS, BBO
| ID: biblio-1056838
ABSTRACT
Abstract Objective:
To investigate the correlation Cluster of Differentiation 4+ (CD4+) counts with a high prevalence of dental caries in Children Living with Perinatal Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (CLWPHA). Material andMethods:
An analytical observational research with a cross-sectional design was conducted at Tertiary General Hospital, Surabaya, Indonesia. Randomized total sampling consisted of 29 CLWPHA 1-12 years old at outpatient ward Infectious Disease Intermediate Unit (UPIPI) Tertiary General Hospital Doctor Soetomo Surabaya. Demographic details and recent CD4+ counts obtained from medical records. Decayed, missing, filled teeth (dmft) in primary teeth and DMFT in permanent teeth index were used. Pearson's and Spearman's Correlation test (p<0.05) were performedResults:
Dental caries prevalence was 86.2%; meanwhile, the dmft/DMFT index score found were high (8.2 / 6.3). CD4+ count and caries showed significant correlation (r=-0.394, p<0.05). Tooth brushing frequency with caries showed a significant correlation (r=-0.419, p<0.05). Antiretroviral (ARV) therapy and caries showed an insignificant negative correlation (p<0.05)Conclusion:
The high prevalence of dental caries in CLWPHA correlated with low CD4+ counts.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Child
/
Acquired Immunodeficiency Syndrome
/
HIV
/
CD4 Lymphocyte Count
/
Dental Caries
Type of study:
Controlled clinical trial
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2019
Type:
Article
Affiliation country:
Indonesia
Institution/Affiliation country:
RSUD/ID
/
Universitas Airlangga/ID
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