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Metabolic syndrome in pregnancy and postpartum: prevalence and associated factors
Lima, Maria do Carmo Pinto; Melo, Adriana Suely Oliveira; Sena, Aline Silva Santos; Barros, Vivianne de Oliveira; Amorim, Melania Maria Ramos.
  • Lima, Maria do Carmo Pinto; Instituto Paraibano de Pesquisa Joaquim Amorim Neto. Campina Grande. BR
  • Melo, Adriana Suely Oliveira; Instituto Paraibano de Pesquisa Joaquim Amorim Neto. Campina Grande. BR
  • Sena, Aline Silva Santos; Instituto Paraibano de Pesquisa Joaquim Amorim Neto. Campina Grande. BR
  • Barros, Vivianne de Oliveira; Instituto Paraibano de Pesquisa Joaquim Amorim Neto. Campina Grande. BR
  • Amorim, Melania Maria Ramos; Instituto Paraibano de Pesquisa Joaquim Amorim Neto. Campina Grande. BR
Rev. Assoc. Med. Bras. (1992) ; 65(12): 1489-1495, Dec. 2019. tab
Article in English | LILACS | ID: biblio-1057094
ABSTRACT
SUMMARY OBJECTIVE Evaluate the prevalence of metabolic syndrome (MS) and the main associated maternal factors in women without pre-gestational conditions, in early pregnancy and in the immediate postpartum. METHODS Two hundred pregnant women were evaluated at the 16th week of pregnancy, and 187 were reassessed postpartum. MS was diagnosed according to the criteria by the National Cholesterol Education Program Adult Treatment Panel III. In addition to the diagnostic criteria, anthropometric measures, blood pressure, metabolic profile, and visceral and subcutaneous fat thickness (by ultrasonography) were collected from the pregnant woman. The student's t-test was used to compare the prevalence of MS and its components in the 16th week and in the postpartum. Multiple logistic regression was performed to identify the principal factors associated with the syndrome. RESULTS The prevalence of the MS was 3.0% in early pregnancy and 9.7% postpartum (p=0.01). Following multiple logistic regression, the prepregnancy body mass index (BMI) (p=0.04) and high-density lipoprotein cholesterol (HDL-c) (p=0.02) remained associated with MS at 16 weeks, and triglyceride levels evaluated in postpartum (p<0.001) with MS in postpartum. CONCLUSION The frequency of the MS was high in the immediate postpartum. The factors associated were prepregnancy BMI and HDL-c at the 16th week, as well as triglyceride levels postpartum.
RESUMO
RESUMO OBJETIVO Avaliar a prevalência da SM e os principais fatores maternos associados em mulheres sem doenças pré-gestacionais, no início da gravidez e no pós-parto imediato. MÉTODOS Foram avaliadas 200 mulheres na 16a semana de gravidez, sendo 187 reavaliadas no pós-parto. A SM foi diagnosticada de acordo com os critérios do National Cholesterol Education Program Adult Treatment Panel III. Além dos critérios diagnósticos da síndrome, foram coletadas medidas antropométricas, pressão arterial, perfil metabólico e espessura de gordura visceral e subcutânea (através de ultrassonografia) da gestante. O teste t de Student foi usado para comparar a prevalência de SM e dos seus componentes nos dois momentos. Os modelos de regressão logística múltipla, para investigar os principais fatores associados à síndrome na 16a semana de gestação e no pós-parto. RESULTADOS A prevalência da SM foi de 3,0% no início da gravidez e 9,7% no pós-parto (p=0,01). O índice de massa corporal (IMC) pré-gravídico (p=0,04) e o colesterol lipoproteínas de alta densidade (HDL-c) (p=0,02) permaneceram associados à SM na 16a semana. Após o parto, os níveis de triglicerídeos permaneceram associados à SM no pós-parto (p<0,001). CONCLUSÃO A prevalência da SM foi alta no pós-parto imediato e os fatores associados à síndrome foram IMC pré-gravídico e HDL-c na 16a semana, e níveis triglicerídeos no pós-parto.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pregnancy Complications / Metabolic Syndrome / Postpartum Period Type of study: Etiology study / Prevalence study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Instituto Paraibano de Pesquisa Joaquim Amorim Neto/BR

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Full text: Available Index: LILACS (Americas) Main subject: Pregnancy Complications / Metabolic Syndrome / Postpartum Period Type of study: Etiology study / Prevalence study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Pregnancy Country/Region as subject: South America / Brazil Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Instituto Paraibano de Pesquisa Joaquim Amorim Neto/BR