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The relationship between tumor budding and survival in colorectal carcinomas
Ozer, Songul Peltek; Barut, Saime Gul; Ozer, Bahri; Catal, Oguz; Sit, Mustafa.
  • Ozer, Songul Peltek; Abant İzzet Baysal University Hospital. Department of Pathology. Bolu. TR
  • Barut, Saime Gul; Haseki Training and Research Hospital. Department of Pathology. İstanbul. TR
  • Ozer, Bahri; Abant İzzet Baysal University Hospital. Department of General Surgery. Bolu. TR
  • Catal, Oguz; Abant İzzet Baysal University Hospital. Department of General Surgery. Bolu. TR
  • Sit, Mustafa; Abant İzzet Baysal University Hospital. Department of General Surgery. Bolu. TR
Rev. Assoc. Med. Bras. (1992) ; 65(12): 1442-1447, Dec. 2019. tab
Article in English | LILACS | ID: biblio-1057096
ABSTRACT
SUMMARY OBJECTIVE Tumor budding is a parameter that is increasingly understood in colorectal carcinomas. We aimed to investigate the relationship between tumor budding, prognostic factors, and survival METHODS A total of 185 patients who had undergone colorectal surgery were observed. Tumor budding, the tumor budding score, and the relationship between these and prognostic factors, and survival investigated. RESULTS Tumor budding was found in 91 (49.2%) cases. The relationship between the tumor budding score and histological grade, lymphovascular invasion, perineural invasion, pathological lymph node stage, and mortality rates were significant. CONCLUSION In our study, the relationship between tumor budding and survival is very strong. Considering these findings and the literature, the prognostic significance of tumor budding becomes clear and should be stated in pathology reports.
RESUMO
RESUMO OBJETIVO Brotamento de tumor é um parâmetro que é cada vez mais conhecido em carcinomas colorretais. Nosso objetivo foi investigar a relação entre brotamento tumoral e fatores prognósticos e sobrevida. MÉTODOS Um total de 240 pacientes observados, submetidos à cirurgia colorretal. Brotamento de tumor, escore de brotamento tumoral e a relação entre estes e fatores prognósticos, sobrevida investigada. RESULTADOS Brotamento de tumores foi encontrado em 91 (49,2%) casos. A relação entre o escore de brotamento tumoral e o grau histológico, invasão linfovascular, invasão perineural, estadiamento linfonodal patológico e taxas de mortalidade foram significativas. CONCLUSÃO Em nosso estudo, a relação entre brotamento tumoral e sobrevida é muito forte. Em conjunto, todos esses achados e literatura são avaliados simultaneamente, o significado prognóstico da brotação do tumor é claramente visto e deve ser indicado nos relatórios de patologia.
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Full text: Available Index: LILACS (Americas) Main subject: Carcinoma / Colorectal Neoplasms Type of study: Observational study / Prognostic study Limits: Female / Humans / Male Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Abant İzzet Baysal University Hospital/TR / Haseki Training and Research Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Carcinoma / Colorectal Neoplasms Type of study: Observational study / Prognostic study Limits: Female / Humans / Male Language: English Journal: Rev. Assoc. Med. Bras. (1992) Year: 2019 Type: Article Affiliation country: Turkey Institution/Affiliation country: Abant İzzet Baysal University Hospital/TR / Haseki Training and Research Hospital/TR