Genotype®MTBDRplus and Xpert®MTB/RIF in the diagnosis of tuberculosis and resistant tuberculosis: cost analysis in a tertiary referral hospital
Rev. Soc. Bras. Med. Trop
;
53: e20190175, 2020. tab
Article
in English
| LILACS
| ID: biblio-1057267
ABSTRACT
Abstract INTRODUCTION:
The present study sought to assess the mean and activity based cost (ABC) of the laboratory diagnosis for tuberculosis through the application of conventional and molecular techniques-Xpert®MTB/RIF and Genotype®MTBDRplus-in a tertiary referral hospital in Brazil.METHODS:
The mean cost and ABC formed the basis for the cost analysis of the TB laboratory diagnosis.RESULTS:
The mean cost and ABC were US$ 4.00 and US$ 3.24, respectively, for a bacilloscopy; US$ 6.73 and US$ 5.27 for a Lowenstein-Jensen (LJ) culture; US$ 105.42 and US$ 76.56 for a drug sensitivity test (DST)-proportions method (PM) in LJ; US$ 148.45 and US$ 136.80 for a DST-BACTECTM MGITTM 960 system; US$ 11.53 and US$ 9.89 for an Xpert®MTB/RIF; and US$ 84.21 and US$ 48.38 for a Genotype®MTBDRplus.CONCLUSIONS:
The mean cost and ABC proved to be good decision-making parameters in the diagnosis of TB and MDR-TB. The effective implementation of algorithms will depend on the conditions at each location.
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Index:
LILACS (Americas)
Main subject:
Tuberculosis, Pulmonary
/
Tuberculosis, Multidrug-Resistant
/
Costs and Cost Analysis
/
Mycobacterium tuberculosis
Type of study:
Diagnostic study
/
Health economic evaluation
/
Prognostic study
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federação Hospitalar do Estado de Minas Gerais/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade Federal do Rio de Janeiro/BR
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