Hepatitis B: Prevalence and occult infection in HIV-infected patients
Rev. Soc. Bras. Med. Trop
;
53: e20180533, 2020. tab
Article
in English
| LILACS
| ID: biblio-1057270
ABSTRACT
Abstract INTRODUCTION:
HBV and HIV have identical transmission routes. The aim of this study was to determine the prevalence of HBV in HIV patients and to detect the presence of occult HBV infection.METHODS:
All samples were tested for serology markers and using qPCR.RESULTS:
This study included 232 individuals, out of which 36.6% presented with HBV markers and 11.8% presented with HBsAg or HBV-DNA, including 3 patients that showed OBI.CONCLUSIONS:
We observed a high prevalence of HBV among HIV patients. In addition, the results suggest that OBI can occur in patients with serological profiles that are indicative of past infection. Therefore, the application of molecular tests may enable the identification of infections that are not evident solely based on serology.
Full text:
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Index:
LILACS (Americas)
Main subject:
HIV Infections
/
Hepatitis B virus
/
Hepatitis B
/
Hepatitis B Antibodies
/
Hepatitis B Core Antigens
/
Hepatitis B Surface Antigens
Type of study:
Diagnostic study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2020
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Adolfo Lutz/BR
/
Universidade de São Paulo/BR
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