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Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption
Ribeiro, Ághata Cardoso da Silva; Crozatti, Márcia Terezinha Lonardoni; Silva, Adilson Aderito da; Macedo, Rodrigo Spineli; Machado, Antonia Maria de Oliveira; Silva, Antonio Távora de Albuquerque.
Affiliation
  • Ribeiro, Ághata Cardoso da Silva; Universidade Federal de São Paulo. Instituto de Ciências Ambientais, Químicas e Farmacêuticas. Diadema. BR
  • Crozatti, Márcia Terezinha Lonardoni; Universidade Federal de São Paulo. Instituto de Ciências Ambientais, Químicas e Farmacêuticas. Diadema. BR
  • Silva, Adilson Aderito da; Universidade Presbiteriana Mackenzie. Centro de Ciências Sociais e Aplicadas. São Paulo. BR
  • Macedo, Rodrigo Spineli; Universidade Federal de São Paulo. Hospital Universitário da UNIFESP. São Paulo. BR
  • Machado, Antonia Maria de Oliveira; Universidade Federal de São Paulo. Departamento de Medicina. Laboratório Central do Hospital São Paulo. São Paulo. BR
  • Silva, Antonio Távora de Albuquerque; Universidade Federal de São Paulo. Instituto de Ciências Ambientais, Químicas e Farmacêuticas. Diadema. BR
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;53: e20180498, 2020. tab
Article in En | LILACS | ID: biblio-1057281
Responsible library: BR1.1
ABSTRACT
Abstract

INTRODUCTION:

Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance.

METHODS:

Data were obtained from ICUs between 2010 and 2013.

RESULTS:

P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem, meropenem, and polymyxin B.

CONCLUSIONS:

Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multi-drug resistance.
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Full text: 1 Index: LILACS Main subject: Pseudomonas aeruginosa / Pseudomonas Infections / Cross Infection Type of study: Prevalence_studies / Risk_factors_studies Limits: Humans Language: En Journal: Jornal brasileiro de medicina tropical / Rev Soc Bras Med Trop / Rev. Soc. Bras. Med. Trop / Rev. Soc. Bras. Med. Trop. (Online) / Revista da Sociedade Brasileira de Medicina Tropical (Impresso) Journal subject: MEDICINA TROPICAL Year: 2020 Type: Article
Fulltext
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Full text: 1 Index: LILACS Main subject: Pseudomonas aeruginosa / Pseudomonas Infections / Cross Infection Type of study: Prevalence_studies / Risk_factors_studies Limits: Humans Language: En Journal: Jornal brasileiro de medicina tropical / Rev Soc Bras Med Trop / Rev. Soc. Bras. Med. Trop / Rev. Soc. Bras. Med. Trop. (Online) / Revista da Sociedade Brasileira de Medicina Tropical (Impresso) Journal subject: MEDICINA TROPICAL Year: 2020 Type: Article