Chemical constituents from the fruits of Schisandra sphenanthera and their cytotoxicity activity
Rev. bras. farmacogn
;
29(5): 578-581, Sept.-Oct. 2019. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1057839
ABSTRACT
Abstract Schisandra sphenanthera Rehder & E.H. Wilson, Schisandraceae, is well known as a type of traditional medicine for the treatment of hepatitis, diarrhea and insomnia in Asia. It was also reported to have antiviral and anti-HIV activities. Using various chromatographic resins and isolation techniques, a new lignan (1), erythro-4-(3,4-dimethoxyphenyl)-4-hydroxy-3-methylbutan-2yl-3,4-dimethoxybenzoate, along with fifteen known compounds, were isolated from fruits of S. sphenanthera. The structures of the compounds were identified by extensive spectroscopic and spectrometric methods including 1D and 2D NMR and MS data. All the isolated compounds were evaluated for their cytotoxicity activity against Hela, HepG2 and HCT-116 cells. Among them, compound schisanlactone C showed significant cytotoxicity activity.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2019
Type:
Article
/
Project document
Affiliation country:
South Korea
/
Vietnam
Institution/Affiliation country:
Gyengnam National University of Science and Technology/KR
/
Institute of Marine Biochemistry/VN
/
Yonsei University/KR
Similar
MEDLINE
...
LILACS
LIS