Determination of orcinol glucoside by LC-MS in Curculigo orchioides and its application to a pharmacokinetic study
Rev. bras. farmacogn
;
29(6): 744-748, Nov.-Dec. 2019. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1057858
ABSTRACT
ABSTRACT This study was designed to explore the pharmacokinetic regularity of the plasma concentration, tissue distribution and excretion of orcinol glucoside from aqueous extracts of raw and processed Curculigo orchioides Gaertn., Hypoxidaceae. The experiment first used an ultrahigh-performance liquid chromatography-tandem mass spectrometry approach with multiple reaction monitoring and a positive mode to separate orcinol glucoside from naringin to obtain the plasma concentration curves, bar graph of tissue distribution and excretion curves. These results might be beneficial for reasonable clinical application of C. orchioides and for further development of its wine and salt-processing mechanism.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2019
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
Liaoning University of Traditional Chinese Medicine/CN
Similar
MEDLINE
...
LILACS
LIS