Cuantificación de esteatosis hepática no alcohólica por resonancia magnética / Quantification of liver fat infiltration by magnetic resonance
Rev. méd. Chile
;
147(7): 821-827, jul. 2019. tab, graf
Article
in Spanish
| LILACS
| ID: biblio-1058610
ABSTRACT
Background:
A simple and inexpensive method is required to assess fatty infiltration of the liver non-invasively.Aim:
To develop and compare different methods to quantify liver fat by magnetic resonance and compare it against ultrasound. Material andMethods:
Three algorithms were implemented region growing (RG), graph cuts (GC) and hierarchical (HR), all based on the IDEAL method to obtain water and fat images. Using these images, the proton density fat fraction (PDFF) was calculated. The three methods were tested in phantoms with known fat percentages and later on we acquired images from 20 volunteers with an ultrasound diagnosis of fatty liver disease in different stages. For everyone, the PDFF of the nine liver segments was determined.Results:
In phantoms, the mean error between the real fat percentage and the value obtained through the three methods was −1,26, −1 and −0,8 for RG, GC and HR, respectively. The hierarchical method was more precise and efficient to obtain PDFF. The results in volunteers revealed that ultrasound showed errors categorizing the severity of hepatic steatosis in more than 50% of volunteers.Conclusions:
We developed a tool for magnetic resonance, which allows to quantify fat in the liver. This method is less operator dependent than ultrasound and describes the heterogeneity in the fat distribution along the nine hepatic segments.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adipose Tissue
/
Non-alcoholic Fatty Liver Disease
/
Liver
Type of study:
Diagnostic study
Limits:
Adult
/
Aged
/
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2019
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Centros de Estudios Clínicos e Investigaciones Médicas/CL
/
Naturalis. Consorcio de Investigación/CL
/
Pontificia Universidad Católica de Chile/CL
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