A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers
Braz. j. infect. dis
;
23(6): 395-409, Nov.-Dec. 2019. tab, graf
Article
in English
| LILACS
| ID: biblio-1089309
ABSTRACT
ABSTRACT In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early diagnosis and best clinical management of IFDs are also presented. This document summarizes practical recommendations that will certainly help pediatricians to best treat their patients suffering of invasive fungal diseases.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Hematologic Neoplasms
/
Invasive Fungal Infections
Type of study:
Controlled clinical trial
/
Etiology study
/
Practice guideline
/
Screening study
Limits:
Child
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Grupo em Defesa da Criança com Câncer/BR
/
Hospital Infantil Darcy Vargas/BR
/
Hospital Infantil Sabará/BR
/
Hospital Samaritano de São Paulo/BR
/
Hospital Santa Marcelina TUCA/BR
/
Hospital das Clínicas de Curitiba/BR
/
Hospital das Clínicas de Porto Alegre/BR
/
Instituto de Oncologia Pediátrica/BR
/
Pro-Imagem medicina diagnóstica Ribeirão Preto/BR
/
Santa Casa de Belo Horizonte/BR
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