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Catheter-related infection due to Papiliotrema laurentii in an oncologic patient: Case report and systematic review
Londero, Marcos Rech; Zanrosso, Crisley Dossin; Corso, Leandro Luis; Michelin, Lessandra; Soldera, Jonathan.
  • Londero, Marcos Rech; Hospital Virvi Ramos. Internal Medicine. Caxias do Sul. BR
  • Zanrosso, Crisley Dossin; Hospital Virvi Ramos. Internal Medicine. Caxias do Sul. BR
  • Corso, Leandro Luis; Universidade de Caxias do Sul. Caxias do Sul. BR
  • Michelin, Lessandra; Universidade de Caxias do Sul. Caxias do Sul. BR
  • Soldera, Jonathan; Universidade de Caxias do Sul. Caxias do Sul. BR
Braz. j. infect. dis ; 23(6): 451-461, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1089312
Responsible library: BR1.1
ABSTRACT
ABSTRACT

Background:

Papiliotrema laurentii is one of several non-neoformans cryptococci that have rarely been associated with human infection, since it was previously considered saprophyte and thought to be non-pathogenic to humans. Nevertheless, increasing number of reports of human infection have emerged in recent years, mostly in oncologic patients.

Aim:

To report a case of a female patient with pyloric obstructive cancer with a catheter-related Papiliotrema laurentii blood stream infection and systematically review the available evidence on P. laurentii infection in humans.

Methods:

Retrieval of studies was based on Medical Subject Headings and Health Sciences Descriptors, which were combined using Boolean operators. Searches were run on the electronic databases Scopus, Web of Science, MEDLINE (PubMed), BIREME (Biblioteca Regional de Medicina), LILACS (Latin American and Caribbean Health Sciences Literature), Cochrane Library for Systematic Reviews and Opengray.eu. There was no language or date of publication restrictions. The reference lists of the studies retrieved were searched manually.

Results:

The search strategy retrieved 1703 references. In the final analysis, 31 references were included, with the description of 35 cases. Every patient but one had a previous co-morbidity - 48.4 % of patients had a neoplasm. Amphotericin B was the most used treatment and only a single case of resistance to it was reported. Most patients were cured of the infection.

Conclusion:

P. laurentii infection in humans is usually associated to neoplasia and multiple co-morbidities, and amphotericin B seems to be a reliable agent for treatment.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Stomach Neoplasms / Catheter-Related Infections Type of study: Case report / Etiology study / Systematic reviews Limits: Aged / Female / Humans Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Virvi Ramos/BR / Universidade de Caxias do Sul/BR

Full text: Available Index: LILACS (Americas) Main subject: Stomach Neoplasms / Catheter-Related Infections Type of study: Case report / Etiology study / Systematic reviews Limits: Aged / Female / Humans Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2019 Type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital Virvi Ramos/BR / Universidade de Caxias do Sul/BR