Hyptis brevipes and Paullinia pinnata extracts and their fractions presenting activity against Mycobacterium abscessos SubSP. massiliense
Rev. patol. trop
;
48(3): 148-160, 2019.
Article
in English
| LILACS
| ID: biblio-1096710
ABSTRACT
Medicinal plants are of great interest for the discovery of new biomolecules with diversified effects. Over the last decade different outbreaks caused by Mycobacterium abscessos subsp. Massiliense have been reported, evidencing it as an important emerging pathogen in underdeveloped countries. This study investigated the antimycobacterial activity of six Brazilian medicinal plant extracts and their fractions. Hyptis brevipes, Tocoyena formosa, Randia armata, Paullinia pinnata, La foensia pacari And Anadenanthera colubrina were evaluated against M. a. massiliense. Total extracts from the medicinal plants H. brevipes, T. formosa, P. pinnata and L. pacari presented a minimal bactericidal concentration of 1 mg/mL. After fractioning, the ethanolic fractions from H. brevipes and P. pinnata presented bactericidal activity, and the ethyl acetate fraction from H. brevipes and T. formosa presented antimycobacterial action. The best bactericidal function of all plant fractions was the ethanolic, which contained rutin and rosmarinic acid that were shown to have microbicidal activity.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plants, Medicinal
/
Hyptis
/
Paullinia
/
Biodiversity
/
Mycobacterium abscessus
Language:
English
Journal:
Rev. patol. trop
Journal subject:
Tropical Medicine
/
Pathology
Year:
2019
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Goiás/BR
/
Universidade Federal do Mato Grosso do Sul/BR
/
Universidade Fedral do Mato Grosso do Sul/BR
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