Your browser doesn't support javascript.
loading
Abordagem diagnóstica e de manuseio da pouchite em doença inflamatória intestinal / Diagnostic and management approach to pouchitis in inflammatory bowel disease
Sedano, Rocío; Nuñez, Paulina; Quera, Rodrigo.
  • Sedano, Rocío; Universidad de Chile. Hospital Clínico. Internal Medicine Departament. Santiago. CL
  • Nuñez, Paulina; Universidad de Chile. Hospital San Juan de Dios. Gastroenterology Section. Santiago. CL
  • Quera, Rodrigo; Clínica Las Condes. Gastroenterology Department. Inflammatory Bowel Disease Program. Santiago. CL
Arq. gastroenterol ; 57(1): 100-106, Jan.-Feb. 2020. graf
Article in English | LILACS | ID: biblio-1098049
ABSTRACT
ABSTRACT In patients with ulcerative colitis refractory to medical therapy, total proctocolectomy and posterior ileal-anal pouch anastomosis is the standard surgical therapy. One of the possible complications is pouchitis. Depending on the duration of the symptoms, it can be classified as acute, recurrent, or chronic. The latter, according to the response to therapy, can be defined as antibiotic-dependent or refractory. The treatment of pouchitis is based on the use of antibiotics and probiotics. Thiopurine and biological therapy have been suggested in patients with refractory pouchitis. Special care should be taken in the endoscopic surveillance of these patients, especially if they present risk factors such as dysplasia or previous colorectal cancer, primary sclerosing cholangitis or ulcerative colitis for more than 10 years.
RESUMO
RESUMO Em pacientes com colite ulcerativa refratária à terapia médica, a proctocolectomia total e anastomose de bolsa ileal-anal posterior é a terapia cirúrgica padrão. Uma das possíveis complicações é a pouchite. Dependendo da duração dos sintomas, pode ser classificado como aguda, recorrente ou crônica. Esta última, de acordo com a resposta à terapia, pode ser definida como dependente de antibióticos ou refratária a eles. O tratamento da pouchite baseia-se no uso de antibióticos e probióticos. A thiopurina e a terapia biológica têm sido sugeridas em pacientes com pouchite refratária. Um cuidado especial deve ser tomado na vigilância endoscópica desses pacientes, especialmente se apresentarem fatores de risco, como displasia ou câncer colorretal anterior, colangite esclerosante primária ou colite ulcerativa por mais de 10 anos.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Colitis, Ulcerative / Proctocolectomy, Restorative / Pouchitis Type of study: Diagnostic study / Etiology study / Risk factors Limits: Humans Language: English Journal: Arq. gastroenterol Journal subject: Gastroenterology Year: 2020 Type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Las Condes/CL / Universidad de Chile/CL

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Colitis, Ulcerative / Proctocolectomy, Restorative / Pouchitis Type of study: Diagnostic study / Etiology study / Risk factors Limits: Humans Language: English Journal: Arq. gastroenterol Journal subject: Gastroenterology Year: 2020 Type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Las Condes/CL / Universidad de Chile/CL